Evidence map›Paper›PMID 39595928›Full record

ReviewInternational journal of molecular sciences2024

High Blood Pressure and Impaired Brain Health: Investigating the Neuroprotective Potential of Magnesium.

Khawlah Alateeq, Erin I Walsh, Nicolas Cherbuin

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Khawlah AlateeqNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0002-0792-7357
Erin I WalshNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0001-8941-0046
Nicolas CherbuinNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0001-6481-0748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High blood pressure (BP) is a significant contributor to the disease burden globally and is emerging as an important cause of morbidity and mortality in the young as well as the old. The well-established impact of high BP on neurodegeneration, cognitive impairment, and dementia is widely acknowledged. However, the influence of BP across its full range remains unclear. This review aims to explore in more detail the effects of BP levels on neurodegeneration, cognitive function, and dementia. Moreover, given the pressing need to identify strategies to reduce BP levels, particular attention is placed on reviewing the role of magnesium (Mg) in ageing and its capacity to lower BP levels, and therefore potentially promote brain health. Overall, the review aims to provide a comprehensive synthesis of the evidence linking BP, Mg and brain health. It is hoped that these insights will inform the development of cost-effective and scalable interventions to protect brain health in the ageing population.

Indexed as

BrainHypertensionMagnesiumNeuroprotective AgentsAgingAnimalsBlood PressureCognitive DysfunctionHumansMagnesiumNeuroprotective Agentsblood pressurebrain ageingdementiamagnesium (Mg)

Identifiers

PMID39595928
PMCPMC11594239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.