Evidence map›Paper›PMID 39595927›Full record

ArticleInternational journal of molecular sciences2024

Is Osteopontin a Reliable Biomarker for Endometriosis?

Aleksandra Zygula, Kamil Kiecka, Anna Sankiewicz, Mariusz Kuzmicki, Michal Ciebiera, Tadeusz Issat, Wojciech Drygas, Krzysztof Cendrowski, Ewa Gorodkiewicz, Piotr Laudanski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aleksandra ZygulaOVIklinika Infertility Center, 01-377 Warsaw, Poland.
Kamil KieckaFaculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
Anna SankiewiczBioanalysis Laboratory, Faculty of Chemistry, University of Bialystok, 15-328 Bialystok, Poland.
Mariusz KuzmickiDepartment of Gynecology and Gynecological Oncology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Michal CiebieraSecond Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, 00-189 Warsaw, Poland.ORCID 0000-0001-5780-5983
Tadeusz IssatDepartment of Obstetrics and Gynecology, Institute of Mother and Child in Warsaw, 01-211 Warsaw, Poland.ORCID 0000-0002-3647-3550
Wojciech DrygasWorld Institute for Family Health, Calisia University, 62-800 Kalisz, Poland.
Krzysztof CendrowskiDepartment of Obstetrics, Gynecology and Gynecological Oncology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Ewa GorodkiewiczBioanalysis Laboratory, Faculty of Chemistry, University of Bialystok, 15-328 Bialystok, Poland.
Piotr LaudanskiOVIklinika Infertility Center, 01-377 Warsaw, Poland.

Funding

the Polish Ministry of Health; the international project acronym TRENDO, co-funded by the funds of the Ministry of Science and Higher Education program entitled "PMW" in the years 2021-2025; contract No. 5216/H2020/2022/2. Polish Ministry of Health no. 6/6/ 4/1/NPZ/2017/1210/13522; TRENDO grant no. 101008193,the Ministry of Science and Higher Education program entitled "PMW" in the years 2021-2025; contract No. 5216/H2020/2022/2.
6 · The paper itself

Abstract

This study aimed to evaluate the concentration of osteopontin in peritoneal fluid and plasma as potential biomarkers for diagnosing endometriosis. Osteopontin levels were measured using surface plasmon resonance imaging (SPRI) biosensors in patients suspected of having endometriosis. Plasma samples were collected from 120 patients, and peritoneal fluid was collected from 86 patients. Based on the detection of endometriosis lesions during laparoscopy, participants were divided into a study group (patients with endometriosis) and a control group (patients without endometriosis). The results showed no significant differences in plasma osteopontin levels between women with endometriosis and the control group (19.86 ± 6.72 ng/mL vs. 18.39 ± 4.46 ng/mL,

Indexed as

Ascitic FluidBiomarkersEndometriosisOsteopontinAdultCase-Control StudiesFemaleHumansBiomarkersOsteopontinSPP1 protein, humandiagnosisendometriosisinfertilityosteopontinperitoneal fluidplasmaSPRI

Identifiers

PMID39595927
PMCPMC11593430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.