Evidence map›Paper›PMID 39595829›Full record

ArticleBrain sciences2024

Atypical Brain Connectivity During Pragmatic and Semantic Language Processing in Children with Autism.

Amparo V Márquez-García, Vasily A Vakorin, Nataliia Kozhemiako, Grace Iarocci, Sylvain Moreno, Sam M Doesburg

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecular dynamics of Brodmann Area 22 in development and autism.bioRxiv : the preprint server for biology · 2026
    Article
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Amparo V Márquez-GarcíaDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0001-7356-6660
Vasily A VakorinDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0003-0489-1552
Nataliia KozhemiakoDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Grace IarocciDepartment of Psychology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Sylvain MorenoDepartment of School of Interactive Arts & Technology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Sam M DoesburgDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.

Funding

CIHR MOP-136935
6 · The paper itself

Abstract

BACKGROUND/

objectivesChildren with Autism Spectrum Disorder (ASD) face challenges in social communication due to difficulties in considering context, processing information, and interpreting social cues. This study aims to explore the neural processes related to pragmatic language communication in children with ASD and address the research question of how functional brain connectivity operates during complex pragmatic language tasks.

methodsWe examined differences in brain functional connectivity between children with ASD and typically developing peers while they engaged in video recordings of spoken language tasks. We focused on two types of speech acts: semantic and pragmatic.

resultsOur results showed differences between groups during the pragmatic and semantic language processing, indicating more idiosyncratic connectivity in children with ASD in the Left Somatomotor and Left Limbic networks, suggesting that these networks play a role in task-dependent functional connectivity. Additionally, these functional differences were mainly localized to the left hemisphere.

Indexed as

autismfMRIfunctional connectivityidiosyncrasylanguagepragmatic languagesemanticsocial cognitive neuroscience

Identifiers

PMID39595829
PMCPMC11592362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.