Evidence map›Paper›PMID 39595675›Full record

ArticleInternational journal of environmental research and public health2024

Internalizing Pathways to Adolescent Substance Use from Adverse Childhood Experiences.

Michelle G Villar, Nicole M Fava, Robert A Zucker, Elisa M Trucco

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle G VillarWien Center for Alzheimer's, Mount Sinai Medical Center, 4300 Alton Rd, Miami, FL 33140, USA.
Nicole M FavaCenter for Children and Families, Florida International University, 11200 SW 8th Street, Miami, FL 33139, USA.
Robert A ZuckerDepartment of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109, USA.
Elisa M TruccoCenter for Children and Families, Florida International University, 11200 SW 8th Street, Miami, FL 33139, USA.ORCID 0000-0002-9922-8608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mediating role of anxious, depressive, and somatic symptoms was examined in the association between adverse childhood experiences (ACEs) and adolescent substance use, with attention to the unique effects of each set of symptoms within the same model. Adolescents (n = 701) were assessed over time (ages 3-17) in a majority male (70.5%) and white (89.9%) sample. Findings indicate that depressive symptoms mediated the association between ACEs and adolescent cigarette and marijuana use. Although significant indirect effects remained when accounting for externalizing behavior, a novel protective pathway emerged through parent-reported youth anxiety and alcohol use. Assessing internalizing symptoms as separate facets within the same model is critical if we are to inform prevention programs that are tailored to the individual needs of youth who have experienced ACEs.

Indexed as

Adverse Childhood ExperiencesAnxietyDepressionAdolescentAdolescent BehaviorChildChild, PreschoolFemaleHumansMaleSubstance-Related DisordersACEsadolescenceadolescentsadverse childhood experiencesanxietydepressioninternalizing problemssomaticsubstance use

Identifiers

PMID39595675
PMCPMC11594189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.