Evidence map›Paper›PMID 39595588›Full record

ArticleBiomolecules2024

Restored Collagen VI Microfilaments Network in the Extracellular Matrix of CRISPR-Edited Ullrich Congenital Muscular Dystrophy Fibroblasts.

Daniela Benati, Eleonora Cattin, Federico Corradi, Tommaso Ferrari, Eleonora Pedrazzoli, Clarissa Patrizi, Matteo Marchionni, Roberto Bertorelli, Veronica De Sanctis, Luciano Merlini and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniela BenatiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-6599-7193
Eleonora CattinDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0009-0007-3737-2181
Federico CorradiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0009-0006-4926-0411
Tommaso FerrariDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-6014-5813
Eleonora PedrazzoliDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Clarissa PatriziDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Matteo MarchionniDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-1163-3466
Roberto BertorelliNext Generation Sequencing Core Facility Department of Cellular, Computational and Integrative Biomedicine-CIBIO LaBSSAH, University of Trento, 38122 Trento, Italy.ORCID 0000-0002-2541-5419
Veronica De SanctisNext Generation Sequencing Core Facility Department of Cellular, Computational and Integrative Biomedicine-CIBIO LaBSSAH, University of Trento, 38122 Trento, Italy.ORCID 0000-0002-9791-5316
Luciano MerliniDepartment of Biomedical and Neuromotor Science, DIBINEM, University of Bologna, 40136 Bologna, Italy.
Alessandra FerliniSection of Medical Genetics, Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-8385-9870
Patrizia SabatelliCNR-Institute of Molecular Genetics, 40136 Bologna, Italy.
Francesca GualandiUnit of Medical Genetics, Department of Mother and Child, University Hospital S. Anna Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9551-057X
Alessandra RecchiaDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-3467-1094

Funding

Cure CMD Million Dollar Bike Ride Award 2018
6 · The paper itself

Abstract

Collagen VI is an essential component of the extracellular matrix (ECM) composed by α1, α2 and α3 chains and encoded by

Indexed as

Collagen Type VICRISPR-Cas SystemsExtracellular MatrixFibroblastsGene EditingMuscular DystrophiesHumansMutationSclerosisCol6a1 protein, humanCollagen Type VIallele-specific gene editingcollagen VIcollagen VI-related disordersCRISPR/Cas9patient-derived fibroblasts

Identifiers

PMID39595588
PMCPMC11591638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.