Evidence map›Paper›PMID 39595135›Full record

ReviewBiomedicines2024

Oral Mycobiome Alterations in Postmenopausal Women: Links to Inflammation, Xerostomia, and Systemic Health.

Claudia Florina Bogdan-Andreescu, Andreea-Mariana Bănățeanu, Cristina-Crenguţa Albu, Cristian-Viorel Poalelungi, Oana Botoacă, Constantin Marian Damian, Laurențiu Mihai Dȋră, Ştefan-Dimitrie Albu, Matei Georgian Brăila, Emin Cadar and 1 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Black Sea-Derived Biomaterials for Wound-Healing Applications.International journal of molecular sciences · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Enrichment ofFrontiers in immunology · 2026
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudia Florina Bogdan-AndreescuDepartment of Speciality Disciplines, Faculty of Dental Medicine, "Titu Maiorescu" University, 031593 Bucharest, Romania.ORCID 0000-0001-5965-893X
Andreea-Mariana BănățeanuDepartment of Speciality Disciplines, Faculty of Dental Medicine, "Titu Maiorescu" University, 031593 Bucharest, Romania.
Cristina-Crenguţa AlbuDepartment of Genetics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-9783-149X
Cristian-Viorel PoalelungiDepartment of Obstetrics and Gynecology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Oana BotoacăDepartment of Speciality Disciplines, Faculty of Dental Medicine, "Titu Maiorescu" University, 031593 Bucharest, Romania.
Constantin Marian DamianDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Laurențiu Mihai DȋrăDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-1766-0534
Ştefan-Dimitrie AlbuDepartment of Periodontology, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Matei Georgian BrăilaFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Emin CadarFaculty of Pharmacy, "Ovidius" University, 900470 Constanta, Romania.ORCID 0000-0002-0085-2081
Anca Daniela BrăilaDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral mycobiome plays a critical role in maintaining oral and systemic health, with its composition and function influenced by various physiological and environmental factors. This descriptive review explores the changes in the oral mycobiome among postmenopausal women, examining how aging and associated inflammatory processes contribute to these alterations. These changes are linked to an increased prevalence of xerostomia, oral dysbiosis, and inflammation, which can negatively impact both oral and systemic health. We discuss the impact of hormonal fluctuations and immune senescence on fungal diversity and abundance, highlighting key species implicated in oral and systemic diseases. The review also examines the role of systemic conditions and medications, which are common in postmenopausal women, in further exacerbating oral mycobiome alterations. Lastly, it highlights the need for future research to better understand these interactions and develop targeted therapeutic strategies. The current literature indicates a significant association between menopausal status, age-related mycobiome shifts, and increased inflammatory responses, suggesting potential pathways for intervention.

Indexed as

hormonal changesinflammationmedicationoral mycobiomepostmenopausal womenxerostomia

Identifiers

PMID39595135
PMCPMC11592264

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.