Evidence map›Paper›PMID 39594951›Full record

ReviewChildren (Basel, Switzerland)2024

Obstructive Sleep Apnea in Pediatrics and Adolescent Women: A Systematic Review of Sex-Based Differences Between Girls and Boys.

Sofía Romero-Peralta, Cristina Rubio, María Castillo-García, Pilar Resano, Miguel Alonso, Esther Solano-Pérez, Laura Silgado, Esther Viejo-Ayuso, Leticia Álvarez-Balado, Olga Mediano

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofía Romero-PeraltaSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Cristina RubioSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
María Castillo-GarcíaSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Pilar ResanoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.ORCID 0000-0001-8518-6446
Miguel AlonsoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Esther Solano-PérezSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Laura SilgadoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Esther Viejo-AyusoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Leticia Álvarez-BaladoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.
Olga MedianoSleep Unit, Pneumology Department, Hospital Universitario de Guadalajara, 19002 Guadalajara, Spain.ORCID 0000-0001-7824-1523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesObstructive sleep apnea (OSA) is marked by repetitive occurrences of upper airway (UA) obstruction during sleep. Morbidities impacting the metabolic, cardiovascular (CV) and neurological systems are correlated with OSA. Only a few studies have described the existence of different characteristics depending on sex and, to date, the girl phenotype in OSA pediatrics is not well known. The objective of this systematic review is to identify the specific phenotype of OSA in pediatric and adolescent females compared to males.

methodsA systematic review was performed. The terms "pediatric sleep apnea" and "sex differences" were used to look for publications using PubMed, the Cochrane Library and Web of Science. INCLUSION CRITERIA: (1) peer-reviewed journal articles written in English; (2) investigations conducted on individuals diagnosed with OSA; and (3) investigations providing information about sex differences. EXCLUSION CRITERIA: (1) studies carried out with individuals aged 18 years and older; (2) studies involving a sample size of fewer than 10 patients; and (3) editorials, letters and case reports.

resultsFifteen studies were included and classified in sections related to sex-based differences.

conclusionsLimited information related to sex-based OSA differences in the pediatric population exists. These differences are conditioned by hormonal status, and are minimal in the premenarcheal period. Moreover, adolescent women present a lower prevalence of obesity and craniofacial alterations, lower OSA severity related to higher UA area and earlier tonsil regression. Hyperactivity is more frequent in boys. Some studies pointed to a higher risk of high diastolic blood pressure in girls than in boys.

Indexed as

childrenobstructive sleep apneaphenotypessex differences

Identifiers

PMID39594951
PMCPMC11593122

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.