Evidence map›Paper›PMID 39594808›Full record

ArticleCancers2024

Factors Affecting Cancer Mortality in Young Adults: Findings from a Prospective Cohort Study.

Ngoan T Le, Yen T-H Pham, Linh T Le, Hang V Dao, Chihaya Koriyama, Toan H Ha, Maureen Lichtveld, Suresh V Kuchipudi, Nhi Y-N Huynh, Dai D Nguyen and 1 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ngoan T LeInstitute of Research and Development, Duy Tan University, Da Nang 550000, Vietnam.ORCID 0000-0001-7862-492X
Yen T-H PhamUniversity of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, PA 15261, USA.
Linh T LeLaboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR, 59045 Paris, France.
Hang V DaoInternal Medicine Faculty, Hanoi Medical University, Hanoi 100000, Vietnam.
Chihaya KoriyamaDepartment of Epidemiology and Preventive Medicine, Graduate School of Medicine and Dental Science, Kagoshima University, Kagoshima 890-0065, Japan.
Toan H HaDepartment of Infectious Disease and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-0574-0804
Maureen LichtveldDepartment of Environmental and Occupational Health, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Suresh V KuchipudiDepartment of Infectious Disease and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Nhi Y-N HuynhSchool of Medicine, International University of Health and Welfare, Narita 324-8501, Japan.
Dai D NguyenSchool of Medicine, International University of Health and Welfare, Narita 324-8501, Japan.
Hung N LuuUniversity of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, PA 15261, USA.ORCID 0000-0002-2172-1849

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0M
Translational Research Training in Cancer Prevention and ControlT32CA186873 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Kathryn H. Schmitz, Jian-Min Yuan · 2014 to 2026
$2.7M
Ministry of Science and Technology 18/FIRST/1a/HMU.NCI NIH HHS P30 CA047904NCI NIH HHS T32 CA186873
6 · The paper itself

Abstract

BACKGROUND/

objectivesCancer incidence in young adults or those aged 15-49 years old has increased during the past decade. Knowledge about the risk factors for cancer-related deaths in young adults is limited, particularly in low- and middle-income countries (LMICs).

methodsThis analysis was based on the Hanoi Prospective Cohort Study, an ongoing study of 39,401 participants aged 15 or older in Northern Vietnam in the 2007-2019 period. A Cox proportional hazard regression model was used to calculate the hazard ratio (HR) and 95% confidence intervals (95% CIs) for the association between potential factors and the risk of cancer-related deaths.

resultsWith a median follow-up of 11.01 years, we identified 164 deaths in young adults out of 554 total deaths. Overall, family history of cancer (HR = 7.34; 95% CI: 3.30-16.36), drinking alcohol (HR = 1.82; 95% CI: 1.18-2.81), and smoking (HR = 2.22; 95% CI: 1.36-3.63) were found to be risk factors, while drinking coffee was found to be a protective factor (HR = 0.49; 95% CI: 0.24-1.00) for cancer-related deaths in young adults. Young male adults were found to be at a higher risk due to excessive cigarette smoking (HR = 1.91; 95% CI: 1.00-3.68) and alcohol consumption (HR = 2.15; 95% CI: 1.32-3.53) than those aged 50 years and older (HR = 1.36 and 95% CI: 0.96-1.93 and 1.27 and 95% CI: 0.97-1.67, respectively). The risk of death from cancer in women compared with men in the young population was twice as high as that in the older population (HR = 1.18 and 95% CI: 0.72-1.94 vs. 0.47 and 95% CI: 0.35-0.63, respectively).

conclusionsOur data suggest that the young Vietnamese population is vulnerable to the risk of cancer-related deaths and that cancer in women will increase rapidly in the future.

Indexed as

cancer mortalityprospective cohort studyrisk factorsVietnamyoung adults

Identifiers

PMID39594808
PMCPMC11593055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.