Evidence map›Paper›PMID 39594806›Full record

ArticleCancers2024

A New Approach of Detecting

Galina Zakharova, Maria Suntsova, Elizaveta Rabushko, Tharaa Mohammad, Alexey Drobyshev, Alexander Seryakov, Elena Poddubskaya, Alexey Moisseev, Anastasia Smirnova, Maxim Sorokin and 5 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. AccurateInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Galina ZakharovaInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-2548-8511
Maria SuntsovaInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Elizaveta RabushkoInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Tharaa MohammadEndocrinology Research Center, 117292 Moscow, Russia.ORCID 0000-0003-4237-0846
Alexey DrobyshevInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Alexander SeryakovMedical Holding SM-Clinic, 105120 Moscow, Russia.
Elena PoddubskayaInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Alexey MoisseevInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Anastasia SmirnovaInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-7546-7436
Maxim SorokinInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0001-7685-3446
Victor TkachevOncobox LLC, 119991 Moscow, Russia.
Alexander SimonovInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Egor GuguchkinInstitute for System Programming of RAS, 109004 Moscow, Russia.ORCID 0000-0001-7885-9892
Evgeny KarpulevichInstitute for System Programming of RAS, 109004 Moscow, Russia.ORCID 0000-0002-6771-2163
Anton BuzdinInstitute for Personalized Oncology, World-Class Research Center "Digital Biodesign and Personalized Healthcare", I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

Funding

Ministry of Science and Higher Education of the Russian Federation within the framework of state support for the creation and development of World-Class Research Centers "Digital biodesign and personalized healthcare" 075-15-2022-304Russian Science Foundation 20-75-10071
6 · The paper itself

Abstract

backgroundIn clinical practice, various methods are used to identify

methodsA total of 906 human cancer biosamples were subjected to analysis using experimental RNAseq data, with the objective of determining the extent of asymmetry in

results

conclusionsRNAseq exon coverage analysis can effectively detect

Indexed as

ALK rearrangementanaplastic lymphoma kinase (ALK)clinical oncologyfusion oncogenereceptor tyrosine kinaseRNA sequencingtumor molecular diagnostics

Identifiers

PMID39594806
PMCPMC11592821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.