Evidence map›Paper›PMID 39594635›Full record

ArticleCells2024

HC-HA/PTX3 from Human Amniotic Membrane Induced Differential Gene Expressions in DRG Neurons: Insights into the Modulation of Pain.

Shao-Qiu He, Chi Zhang, Xue-Wei Wang, Qian Huang, Jing Liu, Qing Lin, Hua He, Da-Zhi Yang, Scheffer C Tseng, Yun Guan

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. CD44 signaling in skin wound healing and regeneration.Journal of translational medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shao-Qiu HeDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Chi ZhangDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Xue-Wei WangDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-1375-7358
Qian HuangDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Jing LiuDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Qing LinDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-8890-800X
Hua HeBioTissue, Inc., Miami, FL 33126, USA.ORCID 0009-0007-2610-2418
Da-Zhi YangAcrogenic Technologies Inc., Rockville, MD 20847, USA.
Scheffer C TsengBioTissue, Inc., Miami, FL 33126, USA.
Yun GuanDepartment of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0003-1321-6655

Funding

Birth Tissue Products for Non-opioid Treatment of Post-surgical PainR01NS117761 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GUAN, YUN · 2020 to 2024
$2.6M
Mechanistic Study of Pain Inhibition by Activation of Non-nociceptive Afferent FibersR01NS110598 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GUAN, YUN · 2019 to 2024
$2.4M
Deciphering the Transcriptional Regulatory Network Controlling RGC Axon Growth to Promote RGC Axon Regeneration and Cell Survival after Axonal InjuryR00EY031742 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI Xuewei Wang · 2024 to 2026
$747k
Deciphering the Transcriptional Regulatory Network Controlling RGC Axon Growth to Promote RGC Axon Regeneration and Cell Survival after Axonal InjuryK99EY031742 · NEI · JOHNS HOPKINS UNIVERSITY · PI WANG, XUEWEI · 2020 to 2023
$326k
NEI NIH HHS K99 EY031742NEI NIH HHS R00 EY031742NIH HHS NS110598NIH HHS NS117761NINDS NIH HHS R01 NS110598NINDS NIH HHS R01 NS117761
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmnionGanglia, SpinalNeuronsAnimalsC-Reactive ProteinGene Expression RegulationHumansMicePainPentraxinsPro-OpiomelanocortinSerum Amyloid P-ComponentC-Reactive ProteinPentraxinsPro-OpiomelanocortinSerum Amyloid P-Componentbioinformaticsdorsal root ganglionhuman birth tissuepainRNA-sequencing

Identifiers

PMID39594635
PMCPMC11592720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.