Evidence map›Paper›PMID 39594633›Full record

ArticleCells2024

Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells.

Alexander V Maltsev, Valeria Ventura Subirachs, Oliver Monfredi, Magdalena Juhaszova, Pooja Ajay Warrier, Shardul Rakshit, Syevda Tagirova, Anna V Maltsev, Michael D Stern, Edward G Lakatta and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Inter-Organellar CaCells · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander V MaltsevNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Valeria Ventura SubirachsNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Oliver MonfrediNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Magdalena JuhaszovaNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Pooja Ajay WarrierNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Shardul RakshitNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Syevda TagirovaNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Anna V MaltsevSchool of Mathematics, Queen Mary University of London, London E1 4NS, UK.ORCID 0000-0003-4139-1004
Michael D SternNational Institute on Aging, NIH, Baltimore, MD 21224, USA.ORCID 0000-0003-4476-7425
Edward G LakattaNational Institute on Aging, NIH, Baltimore, MD 21224, USA.
Victor A MaltsevNational Institute on Aging, NIH, Baltimore, MD 21224, USA.ORCID 0000-0002-3832-791X

Funding

U-RISE at University of Maryland Baltimore CountyT34GM136497 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI PHYLLIS R ROBINSON · 2020 to 2026
$9.5M
NIA NIH HHS Intramural Research ProgramNIGMS NIH HHS T34 GM136497
6 · The paper itself

Abstract

The rate of spontaneous action potentials (APs) generated by sinoatrial node cells (SANC) is regulated by local Ca

Indexed as

Action PotentialsRyanodine Receptor Calcium Release ChannelSinoatrial NodeAnimalsCalciumCalcium SignalingRabbitsStructure-Activity RelationshipCalciumRyanodine Receptor Calcium Release Channelnumerical modelpacemaker functionryanodine receptorsinoatrial nodeβ adrenergic stimulation

Identifiers

PMID39594633
PMCPMC11592670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.