Evidence map›Paper›PMID 39594608›Full record

ArticleCells2024

Bioengineering the Human Intestinal Mucosa and the Importance of Stromal Support for Pharmacological Evaluation In Vitro.

Matthew Freer, Jim Cooper, Kirsty Goncalves, Stefan Przyborski

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew FreerDepartment of Biosciences, Durham University, Durham DH1 3LE, UK.
Jim CooperEuropean Collection of Authenticated Cell Cultures, Salisbury SP4 0JG, UK.
Kirsty GoncalvesDepartment of Biosciences, Durham University, Durham DH1 3LE, UK.ORCID 0000-0001-6245-4700
Stefan PrzyborskiDepartment of Biosciences, Durham University, Durham DH1 3LE, UK.ORCID 0000-0001-7613-525X

Funding

BBSRC BB/M015645/1
6 · The paper itself

Abstract

Drug discovery is associated with high levels of compound elimination in all stages of development. The current practices for the pharmacokinetic testing of intestinal absorption combine Transwell

Indexed as

Intestinal MucosaStromal CellsBioengineeringCaco-2 CellsFibroblast Growth Factor 7HumansPermeabilityFibroblast Growth Factor 73D cell cultureCaco-2drug discoveryfibroblastintestinekeratinocyte growth factorpharmacologyscaffoldtissue engineering

Identifiers

PMID39594608
PMCPMC11592477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.