Evidence map›Paper›PMID 39594028›Full record

ReviewFoods (Basel, Switzerland)2024

Calcium Transport and Enrichment in Microorganisms: A Review.

Hai Zhou, Yan-Yu Hu, Zhen-Xing Tang, Zhong-Bao Jiang, Jie Huang, Tian Zhang, Hui-Yang Shen, Xin-Pei Ye, Xuan-Ya Huang, Xiang Wang and 4 more

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in microbiology · 2026
    Article
  4. Article
  5. Inter-Organellar CaCells · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hai ZhouDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Yan-Yu HuDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Zhen-Xing TangSchool of Culinary Art, Tourism College of Zhejiang, Hangzhou 311231, China.
Zhong-Bao JiangDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Jie HuangDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Tian ZhangDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Hui-Yang ShenDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Xin-Pei YeDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Xuan-Ya HuangDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Xiang WangDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Ting ZhouDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Xue-Lian BaiDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Qin ZhuDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Lu-E ShiDepartment of Biotechnology, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.

Funding

High Level Major Research Achievements Training program of Tourism College of Zhejiang No. 2024GCC03
6 · The paper itself

Abstract

Calcium is a vital trace element for the human body, and its deficiency can result in a range of pathological conditions, including rickets and osteoporosis. Despite the numerous types of calcium supplements currently available on the market, these products are afflicted with a number of inherent deficiencies, such as low calcium content, poor aqueous solubility, and low human absorption rate. Many microorganisms, particularly beneficial microorganisms, including edible fungi, lactic acid bacteria, and yeast, are capable of absorbing and enriching calcium, a phenomenon that has been widely documented. This opens the door to the potential utilization of microorganisms as novel calcium enrichment carriers. However, the investigation of calcium-rich foods from microorganisms still faces many obstacles, including a poor understanding of calcium metabolic pathways in microorganisms, a relatively low calcium enrichment rate, and the slow growth of strains. Therefore, in order to promote the development of calcium-rich products from microorganisms, this paper provides an overview of the impacts of calcium addition on strain growth, calcium enrichment rate, antioxidant system, and secondary metabolite production. Additionally, it highlights calcium transport and enrichment mechanisms in microorganism cells and offers a detailed account of the progress made on calcium-binding proteins, calcium transport pathways, and calcium storage and release. This paper offers insights for further research on the relevant calcium enrichment in microorganism cells.

Indexed as

applicationcalciumenrichmentmechanismtransport

Identifiers

PMID39594028
PMCPMC11593130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.