Evidence map›Paper›PMID 39593774›Full record

ArticleBioengineering (Basel, Switzerland)2024

Lipid Alterations in Chronic Nonspecific Low Back Pain in the Chinese Population: A Metabolomic and Lipidomic Study.

Wen Tang, Hong-Jiang Wang, Su-Ying Luo, Si-Yun Zhang, Hao Xie, Hua-Qing Chen, Chu-Huai Wang, Zhou Zhang

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wen TangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Hong-Jiang WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Su-Ying LuoDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Si-Yun ZhangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0003-4087-6595
Hao XieDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Hua-Qing ChenDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Chu-Huai WangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0002-8071-9298
Zhou ZhangDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0002-4314-1052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic nonspecific low back pain (cNLBP) accounts for approximately 90% of low back pain cases, affecting 65-80% of the population and significantly impacting life quality and productivity. This condition also leads to substantial financial burden. Although there have been advancements, a comprehensive understanding of the underlying etiology of cNLBP remains elusive, resulting in less than optimal treatment outcomes. This study aimed to examine the correlation between lipid variations and the development of cNLBP. The cohort consisted of 26 healthy volunteers (HV group) and 30 cNLBP patients, with an assessment of metabolites and lipid composition in both groups. Metabolomic results revealed significant alterations in lipid-associated metabolites between the HV and cNLBP groups. Subsequent lipid analysis revealed that monoacylglycerols (MAGs) increased approximately 1.2-fold (

Indexed as

chronic nonspecific low back paindiacylglycerollipidomicmetabolomicmonoacylglycerolphosphatidylserinetriacylglycerol

Identifiers

PMID39593774
PMCPMC11591451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.