Evidence map›Paper›PMID 39593747›Full record

ArticleBioengineering (Basel, Switzerland)2024

A Biologic and Physical Characterization of an Injectable Amniotic Membrane Designed for Treating Diabetic Foot Ulcers.

Kimberly Velarde, Audrey Arvonen, Tatyana Gonzalez, Robert B Diller

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kimberly VelardeAmnio Technology, LLC., 22510 N. 18th Dr., Phoenix, AZ 85027, USA.
Audrey ArvonenAmnio Technology, LLC., 22510 N. 18th Dr., Phoenix, AZ 85027, USA.
Tatyana GonzalezAmnio Technology, LLC., 22510 N. 18th Dr., Phoenix, AZ 85027, USA.
Robert B DillerAmnio Technology, LLC., 22510 N. 18th Dr., Phoenix, AZ 85027, USA.ORCID 0000-0002-7030-1277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlobally, the health and quality of life of millions of people are negatively affected by diabetic foot ulcers (DFUs). To treat these chronic wounds, a novel injectable drug for closing DFUs composed of micronized amniotic membrane was developed. This new therapeutic drug for wound repair expands on traditional allograft therapies by allowing extracellular matrix proteins, growth factors, and cytokines to reach wound anatomies in DFUs that are difficult to treat. The aim of this study was to evaluate the components of the injectable drug.

methodsLiquid chromatography with tandem mass spectrometry and a Quantibody

resultsLiquid chromatography with tandem mass spectrometry and Quantibody

conclusionsCollectively, these data present the potential of a novel injectable drug for the treatment of DFUs.

Indexed as

amniotic membranediabetic foot ulcernovel birth tissue injectablewound healing

Identifiers

PMID39593747
PMCPMC11591430

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.