Evidence map›Paper›PMID 39593729›Full record

ArticleBioengineering (Basel, Switzerland)2024

Identifying Ventricular Dysfunction Indicators in Electrocardiograms via Artificial Intelligence-Driven Analysis.

Hisaki Makimoto, Takayuki Okatani, Masanori Suganuma, Tomoyuki Kabutoya, Takahide Kohro, Yukiko Agata, Yukiyo Ogata, Kenji Harada, Redi Llubani, Alexandru Bejinariu and 6 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Advances in AI Technology in Healthcare.Bioengineering (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hisaki MakimotoCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.ORCID 0000-0002-5302-2874
Takayuki OkataniGraduate School of Information Sciences, Tohoku University, Sendai 980-8577, Japan.
Masanori SuganumaGraduate School of Information Sciences, Tohoku University, Sendai 980-8577, Japan.
Tomoyuki KabutoyaCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.ORCID 0000-0002-5439-4303
Takahide KohroCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.
Yukiko AgataCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.
Yukiyo OgataCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.
Kenji HaradaCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.
Redi LlubaniDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.
Alexandru BejinariuDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.ORCID 0000-0002-4820-3304
Obaida R RanaDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.ORCID 0000-0002-7956-3249
Asuka MakimotoDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.
Elisabetha GharibDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.
Anita MeissnerDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.ORCID 0009-0000-5659-9540
Malte KelmDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.ORCID 0000-0003-0060-1052
Kazuomi KarioCardiovascular Centre, Jichi Medical University, Shimotsuke 329-0498, Japan.

Funding

Taiju Life Social Welfare Foundation the 55th Medical Research Grant FY2022the Cabinet Office, Government of Japan JPJ012425 "the Cross-ministerial Strategic Innovation Promotion Program (SIP) on Integrated Health Care System"
6 · The paper itself

Abstract

Recent studies highlight artificial intelligence's ability to identify ventricular dysfunction via electrocardiograms (ECGs); however, specific indicative waveforms remain unclear. This study analysed ECG and echocardiography data from 17,422 cases in Japan and Germany. We developed 10-layer convolutional neural networks to detect left ventricular ejection fractions below 50%, using four-fold cross-validation. Model performance, evaluated among different ECG configurations (3 s strips, single-beat, and two-beat overlay) and segments (PQRST, QRST, P, QRS, and PQRS), showed two-beat ECGs performed best, followed by single-beat models, surpassing 3 s models in both internal and external validations. Single-beat models revealed limb leads, particularly I and aVR, as most indicative of dysfunction. An analysis indicated segments from QRS to T-wave were most revealing, with P segments enhancing model performance. This study confirmed that dual-beat ECGs enabled the most precise ventricular function classification, and segments from the P- to T-wave in ECGs were more effective for assessing ventricular dysfunction, with leads I and aVR offering higher diagnostic utility.

Indexed as

artificial intelligenceelectrocardiogramventricular dysfunction

Identifiers

PMID39593729
PMCPMC11591176

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.