Evidence map›Paper›PMID 39593717›Full record

ArticleBioengineering (Basel, Switzerland)2024

Tetracalcium Phosphate/Monetite/Calcium Sulfate Hemihydrate Biocement for Alveolar Bone Augmentation After Tooth Extraction in Pig Mandible.

Katarína Vdoviaková, Lenka Krešáková, Filip Humeník, Ján Danko, Kristína Čurgali, Andrej Jenča, Andrej Jenča, Adriána Petrášová, Janka Jenčová, Marko Vrzgula and 3 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Katarína VdoviakováDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenskeho 73, 041 81 Košice, Slovakia.ORCID 0000-0001-5727-7180
Lenka KrešákováDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenskeho 73, 041 81 Košice, Slovakia.
Filip HumeníkDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenskeho 73, 041 81 Košice, Slovakia.
Ján DankoDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenskeho 73, 041 81 Košice, Slovakia.ORCID 0000-0001-6871-7583
Kristína ČurgaliDepartment of Histology and Embryology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 83 Košice, Slovakia.ORCID 0000-0002-0179-3132
Andrej JenčaSolmea s.r.o., Bačíkova 7, 040 01 Košice, Slovakia.
Andrej JenčaSolmea s.r.o., Bačíkova 7, 040 01 Košice, Slovakia.ORCID 0000-0003-4501-7407
Adriána PetrášováSolmea s.r.o., Bačíkova 7, 040 01 Košice, Slovakia.
Janka JenčováSolmea s.r.o., Bačíkova 7, 040 01 Košice, Slovakia.
Marko VrzgulaDepartment of Anatomy, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 83 Košice, Slovakia.ORCID 0000-0001-7296-4034
Mária GiretováDivision of Functional and Hybrid Materials, Institute of Materials Research of SAS, Watsonova 47, 040 01 Košice, Slovakia.
Radoslava ŠtulajterováDivision of Functional and Hybrid Materials, Institute of Materials Research of SAS, Watsonova 47, 040 01 Košice, Slovakia.ORCID 0000-0002-4354-8098
Ľubomír MedveckýDivision of Functional and Hybrid Materials, Institute of Materials Research of SAS, Watsonova 47, 040 01 Košice, Slovakia.ORCID 0000-0002-1720-2034

Funding

Slovak Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences 2/0032/23Slovak Research and Development Agency APVV 20-0184
6 · The paper itself

Abstract

A tetracalcium phosphate/monetite/calcium sulfate hemihydrate powder cement mixture (CAS) in the form of a paste was used as a socket preservative to prevent alveolar ridge resorption after the extraction of the second premolar tooth in the mandible of a pig model. During the post-surgery period, the animals were monitored daily. No signs of inflammation, infection, or other complications were observed in the defect site for six months. Six months after surgery, the mandible defects in pigs were evaluated using macroscopic, histological, and radiological techniques. Treatment of the extraction sites with CAS biocement resulted in the uniform filling of the defects with alveolar bone tissue, characterized by a relatively smooth and homogeneous gum surface with no visible biocement residues. The formation of new bone tissue with osteoblasts, osteocytes, and mineralized matrices was confirmed. The results showed the similar morphology, thickness, and complete integration of the newly formed bone with the surrounding tissue. CAS biocement could be an effective material to prevent alveolar bone reduction as well as soft tissue loss and could support dental implant placement with long-term functionality.

Indexed as

cementcompositeshealingpig animal modelsocket preservation

Identifiers

PMID39593717
PMCPMC11591200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.