ArticleRenal failure2024
Inflammation-based scores predict chronic kidney disease progression in patients with chronic kidney disease and chronic heart failure.
Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Systemic Inflammatory Response Index as a Predictor of Postoperative Infectious Complications in Elderly Patients Undergoing Posterior Spinal Instrumentation.Journal of clinical medicine · 2025Article
- Global trends and disparities in the burden of heart failure caused by chronic kidney disease: an analysis of the global burden of disease study 2021.Frontiers in medicine · 2025Article
- Prognostic nutritional index predicts staging and mortality in cardiovascular-kidney-metabolic syndrome.PloS one · 2025Article
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Authors and funding
21 authors.
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Abstract
backgroundInflammation is associated with adverse outcomes of chronic kidney disease (CKD) or chronic heart failure (CHF), but few large data exist. We aimed to explore the clinical associations, and prognostic consequences of inflammation-based scores in patients with CKD and CHF.
methodsThis work was a retrospective cohort study. Glasgow Prognostic Score (GPS), modified Glasgow Prognostic Score (mGPS), Prognostic Nutritional Index (PNI) and Prognostic Index (PI), were used to explore its relationship with CKD progression in patients with CKD stage 1-3b and CHF from the China Renal Data System (CRDS). The composite end point of this study was CKD progression which was defined as eGFR reduction of 40% or progression to end stage renal disease (ESRD).
resultsOf 8491 patients were enrolled. Kaplan-Meier curve showed that compared to the lower inflammation-based scores, the increased scores have a higher rate of CKD progression, whether in GPS, mGPS, PNI or PI (log-rank test,
conclusionsInflammation-based scores, especially PNI may be a useful clinical biomarker for CKD progression in CKD with CHF patients.
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