Evidence map›Paper›PMID 39593222›Full record

ArticleHuman brain mapping2024

Accelerating Heritability, Genetic Correlation, and Genome-Wide Association Imaging Genetic Analyses in Complex Pedigrees.

Brian Donohue, Si Gao, Thomas E Nichols, Bhim M Adhikari, Yizhou Ma, Neda Jahanshad, Paul M Thompson, Francis J McMahon, Elizabeth M Humphries, William Burroughs and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human brain mapping, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Brian DonohueDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Si GaoDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Thomas E NicholsBig Data Science Institute, Department of Statistics, University of Oxford, Oxford, UK.ORCID 0000-0002-4516-5103
Bhim M AdhikariDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Yizhou MaDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Neda JahanshadImaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, California, USA.
Paul M ThompsonImaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, California, USA.
Francis J McMahonHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.
Elizabeth M HumphriesInstitute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
William BurroughsDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Seth A AmentInstitute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
Braxton D MitchellDepartment of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
Tianzhou MaDepartment of Epidemiology and Biostatistics, University of Maryland, Maryland, USA.
Shuo ChenDepartment of Psychiatry, University of Maryland, School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7990-4947
Sarah E MedlandQIMR Berghofer Medical Research Institute, Queensland, Australia.ORCID 0000-0003-1382-380X
John BlangeroDepartment of Human Genetics, University of Texas Rio Grande Valley, School of Medicine, Brownsville, Texas, USA.
L Elliot HongDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.
Peter KochunovDepartment of Psychiatry and Behavioral Sciences, University of Texas, Health Science Center Houston, Houston, Texas, USA.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Mohamad Habes · 2021 to 2026
$24.0M
Workforce Development CoreU54HG013247 · NHGRI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Gladys E. Maestre · 2023 to 2026
$10.5M
Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
Quantitative Trait Locus Mapping in Human PedigreesR37MH059490 · NIMH · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI BLANGERO, JOHN · 2001 to 2010
$6.8M
Rio Grande Valley Alzheimer's Resource Center for Minority Aging Research: Partnerships for ProgressP30AG059305 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Gladys E. Maestre · 2018 to 2026
$5.8M
SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Genetics of Brain Structure and FunctionR01MH078111 · NIMH · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI BLANGERO, JOHN · 2006 to 2014
$4.5M
Imaging Genomics of the Aging BrainR01AG058464 · NIA · YALE UNIVERSITY · PI BLANGERO, JOHN, GLAHN, DAVID C · 2018 to 2022
$3.9M
Towards Multisystem-Brain Successful Aging in Schizophrenia SpectrumR01MH116948 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HONG, L ELLIOT ELLIOT · 2018 to 2022
$3.7M
Lifespan Vascular Biology on White MatterRF1NS114628 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2020 to 2020
$3.1M
NHGRI NIH HHS U54 HG013247NHGRI NIH HHS U54HG013247NIA NIH HHS P30 AG028747NIA NIH HHS P30 AG059305NIA NIH HHS P30AG059305NIA NIH HHS P30 AG066546NIA NIH HHS P30AG066546NIA NIH HHS R01 AG058464NIA NIH HHS R01AG058464NIBIB NIH HHS R01EB01561NIBIB NIH HHS R01 EB015611NIBIB NIH HHS R21 EB001561NIBIB NIH HHS U54 EB020403NIBIB NIH HHS U54EB020403NIDA NIH HHS K01 DA059603NIH HHS S10 OD023696NIMH NIH HHS R01 MH078111NIMH NIH HHS R01 MH116948NIMH NIH HHS R01MH123163NIMH NIH HHS R01 MH133812NIMH NIH HHS R37 MH059490NIMH NIH HHS RF1 MH123163NIMH NIH HHS U54 MH091657NIMH NIH HHS U54MH091657NINDS NIH HHS R01 NS114628NINDS NIH HHS RF1 NS114628
6 · The paper itself

Abstract

National and international biobanking efforts led to the collection of large and inclusive imaging genetics datasets that enable examination of the contribution of genetic and environmental factors to human brains in illness and health. High-resolution neuroimaging (~10

Indexed as

Genome-Wide Association StudyPedigreeBrainFemaleHumansMagnetic Resonance ImagingMaleNeuroimagingPolymorphism, Single NucleotideBig Data geneticsgenetic correlationGWASheritabilitypedigree

Identifiers

PMID39593222
PMCPMC11599162

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.