Evidence map›Paper›PMID 39593101›Full record

Observational studyJournal of neuroengineering and rehabilitation2024

Telerehabilitation using a 2-D planar arm rehabilitation robot for hemiparetic stroke: a feasibility study of clinic-to-home exergaming therapy.

Gabriel Aguirre-Ollinger, Karen Sui Geok Chua, Poo Lee Ong, Christopher Wee Keong Kuah, Tegan Kate Plunkett, Chwee Yin Ng, Lay Wai Khin, Kim Huat Goh, Wei Binh Chong, Jaclyn Ai Mei Low and 5 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05212181 (Smart Robot Therapy for Stroke Upper Limb Rehabilitation), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05212181 completednot on this map

Smart Robot Therapy for Stroke Upper Limb Rehabilitation: A Proof-of-value Trial of Clinic to Home Robotics-assisted Telerehabilitation

TypeobservationalSponsorTan Tock Seng HospitalRan2022 to 2022Enrolled12ConditionsStrokeArmsH-Man
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gabriel Aguirre-OllingerArticares Pte Ltd, 67, Ayer Rajah Crescent, #07-11/12, Singapore, 139950, Singapore. gabriel.aguirre.ollinger@articares.com.ORCID 0000-0003-3834-9171
Karen Sui Geok ChuaInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0000-0001-9809-3425
Poo Lee OngInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0000-0002-0910-6683
Christopher Wee Keong KuahInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0000-0001-6070-3187
Tegan Kate PlunkettInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0009-0007-4596-1525
Chwee Yin NgInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0009-0008-9923-7679
Lay Wai KhinClinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore.ORCID 0000-0001-9181-0372
Kim Huat GohNanyang Business School, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0001-7327-0106
Wei Binh ChongInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0009-0002-1888-8813
Jaclyn Ai Mei LowInstitute of Rehabilitation Excellence (IREx), Tan Tock Seng Hospital Rehabilitation Centre, Singapore, Singapore.ORCID 0009-0000-8241-6269
Malaika MushtaqArticares Pte Ltd, 67, Ayer Rajah Crescent, #07-11/12, Singapore, 139950, Singapore.ORCID 0000-0001-5683-0757
Tengiz SamkharadzeETH Singapore Centre, Singapore, Singapore.ORCID 0000-0003-2969-4555
Simone KagerETH Singapore Centre, Singapore, Singapore.ORCID 0000-0002-1160-1501
Hsiao-Ju ChengETH Singapore Centre, Singapore, Singapore.ORCID 0000-0002-6203-4543
Asif HussainArticares Pte Ltd, 67, Ayer Rajah Crescent, #07-11/12, Singapore, 139950, Singapore.ORCID 0009-0006-3991-301X

Funding

National Health Innovation Centre, Singapore (NHIC) Innovation to Industry (I2I) NHIC-I2I-2104007Temasek Foundation TF REF: TF1920-ATC-01
6 · The paper itself

Abstract

backgroundWe evaluated the feasibility, safety, and efficacy of a 2D-planar robot for minimally supervised home-based upper-limb therapy for post-stroke hemiparesis.

methodsThe H-Man, end effector robot, combined with web-based software application for remote tele-monitoring were evaluated at homes of participants. Inclusion criteria were: strokes > 28 days, Fugl-Meyer Motor Assessment (FMA) > 10-60/66, presence of a carer and absence of medical contraindications. Participants performed self-directed, minimally supervised robotics-assisted therapy (RAT) at home for 30 consecutive days, after 2 therapist-supervised clinic on-boarding sessions. Web-based compliance measures were: accessed sessions of > 20 min/day, training minutes/day and active training hours/30 days. Clinical outcomes at weeks 0, 5 (post-training), 12 and 24 (follow-up) consisted of FMA, Action Research Arm Test (ARAT) and WHO-Stroke Specific Quality of Life (SSQOL). To estimate immediate economic benefits of the home-based robotic therapy, we performed cost-effectiveness analysis (CEA), followed by budget impact analysis (BIA).

resultsAltogether, all 12 participants completed Home-RAT without adverse events; 9 (75.0%) were males, mean (SD) age, 59.4 years (9.5), median (IQR) stroke duration 38.6 weeks (25.4, 79.6) baseline FMA (0-66) 42.1 ± 13.2, ARAT (0-57) 25.4 ± 19.5, SSQOL (0-245) 185.3 ± 32.8. At week 5 follow-up, mean (SD) accessed days were 26.3 days ± 6.4, active training hours of 35.3 h ± 14.7/30 days, or ~ 6 days/week and 77 training minutes ± 20.9/day were observed. Significant gains were observed from baseline across time; ΔFMA 2.4 at week 5 (FMA 44.5, CI 95% 39.7-49.3, p < 0.05) and ΔFMA 3.7 at week 24 (FMA 45.8, CI 95% 40.5-51, p < 0.05); ΔARAT 2.6 at week 5 (ARAT 28.0, CI 95% 19.3-36.7, p < 0.05), and ΔARAT 4.8 at week 24 (ARAT 30.2, CI 95% 21.2-39.1, p < 0.05). At week 5 follow-up, 91% of participants rated their overall experience as satisfied or very satisfied. Incremental CEA observed savings of -S$144/per cure over 24 weeks, BIA-potentially 12% impact reduction over five years.

conclusionsThis study demonstrates the feasibility, acceptability, safety, clinical efficacy, and cost-effectiveness of a home-based, web-enabled telemonitored carer-supervised robotics-aided therapy.

trial registrationNCT05212181  ( https://clinicaltrials.gov ).

Indexed as

Feasibility StudiesParesisRoboticsStroke RehabilitationTelerehabilitationAgedArmCost-Benefit AnalysisExergamingFemaleHumansMaleMiddle AgedStrokeTreatment OutcomeCost-effectivenessEnd effector robotRobotics-assisted therapyStrokeTele-monitoringTelerehabilitationUpper limb

Identifiers

PMID39593101
PMCPMC11590240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.