Evidence map›Paper›PMID 39592569›Full record

ArticleNature communications2024

Ultra-fast photoelectron transfer in bimetallic porphyrin optoelectrode for single neuron modulation.

Jian Chen, Feixiang Chen, Xueli Wang, Hongjun Zhuang, Mengnan Guo, Luo Wang, Junze Xie, Le Zhang, Hao Liu, Yuhan Shi and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Neuro-Cancer Interactions Shape Glioma Intratumoral Heterogeneity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jian Chen *Department of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Feixiang Chen *Department of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Xueli Wang *State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai, China.
Hongjun ZhuangResearch Center for Translational Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Mengnan GuoDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Luo WangDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Junze XieDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Le ZhangInstitute for Biomedical Materials and Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.ORCID 0000-0003-0641-2383
Hao LiuDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Yuhan ShiBaylor College of medicine, Houston, TX, USA.
Jiajia ZhouInstitute for Biomedical Materials and Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.ORCID 0000-0002-0605-5745
Xinjie MaoDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Muyao LvDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.
Xingwu JiangDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China.ORCID 0000-0003-1516-0608
Jinquan ChenState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai, China. jqchen@lps.ecnu.edu.cn.ORCID 0000-0003-0652-1379
Yanyan LiuDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China. liuyyan@fudan.edu.cn.ORCID 0000-0001-6557-8805
Dayong JinInstitute for Biomedical Materials and Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia. dayong.Jin@uts.edu.au.ORCID 0000-0003-1046-2666
Wenbo BuDepartment of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Academy for Engineering and Technology, Fudan University, Shanghai, China. wbbu@fudan.edu.cn.ORCID 0000-0001-6664-3453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shrinking the size of photoelectrodes into the nanoscale will enable the precise modulation of cellular and subcellular behaviors of a single neuron and neural circuits. However, compared to photovoltaic devices, the reduced size causes the compromised efficiencies. Here, we present a highly efficient nanoelectrode based on bimetallic zinc and gold porphyrin (ZnAuPN). Upon light excitation, we observe ultrafast energy transfer (~66 ps) and charge transfer (~0.5 ps) through the porphyrin ring, enabling 97% efficiency in separating and transferring photoinduced charges to single Au-atom centers. Leveraging these isolated Au atoms as stimulating electrode arrays, we achieve significant photocurrent injection in single neurons, triggering action potential with millisecond light pulses. Notably, Extracranial near-infrared light irradiation of the motor cortex induces neuronal firing and enhances mouse movement. These results show the potential of nanoscale optoelectrodes for high spatiotemporal modulation of neuronal networks without the need for gene transfection in optogenetics.

Indexed as

GoldNeuronsOptogeneticsZincAction PotentialsAnimalsElectrodesEnergy TransferLightMiceMotor CortexPorphyrinsGoldPorphyrinsZinc

Identifiers

PMID39592569
PMCPMC11599743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.