Evidence map›Paper›PMID 39592510›Full record

ReviewHealth economics review2024

Economic burden of hepatitis B patients and its influencing factors in China: a systematic review.

Mengxia Yan, Huanhuan Ye, Ying Chen, Huajie Jin, Han Zhong, Bobo Pan, Youqin Dai, Bin Wu

Abstract readReview
In one paragraph

Review in Health economics review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengxia YanDepartment of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Huanhuan YeDepartment of pharmacy, Ningbo Hangzhou Bay Hospital, Ningbo, Zhejiang, 315336, China.
Ying ChenDepartment of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Huajie JinHealth Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's Health Economics (KHE), King's College London, London, UK.
Han ZhongDepartment of Pharmacy, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201112, China.
Bobo PanDepartment of pharmacy, Ningbo Second hospital, Ningbo, Zhejiang, 315010, China.
Youqin DaiDepartment of pharmacy, Ningbo Second hospital, Ningbo, Zhejiang, 315010, China.
Bin WuDepartment of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. scilwsjtu-wb@yahoo.com.

Funding

National Natural Science Foundation of China 72074142Royal Society Sino-British Fellowship Trust International Exchanges Award' from the Royal Society, UK IES\R3\213044
6 · The paper itself

Abstract

BACKGROUND &

aimHepatitis B is globally recognized as a major public health problem that imposes a huge economic burden on society. China is a major country with hepatitis B infection; however, an updated overview of the economic burden of hepatitis B and related diseases in China has not been provided. This study aimed to provide a comprehensive understanding of the economic burden and factors influencing hepatitis B and related diseases by synthesizing the available evidence, with the aim of informing clinical treatment and health decisions.

methodsTwo researchers systematically searched relevant literature published in PubMed, Web of Science, China Knowledge Network, Wanfang Database, and Vip Database from 2002 to 2022, and conducted title and abstract reviews according to the PRISMA guidelines for the development of nerfing criteria, as well as quality evaluation of the included literature.

resultsThirty-three studies were included in the literature. The quality of the included literature was average, with the majority being individual studies and a few group studies, which showed that the annual economic burden per capita of hepatitis B-related diseases was 92,978.34 RMB, with a high proportion of direct and hidden costs, and a large disparity in economic burden between related diseases, with the greatest burden for primary hepatocellular carcinoma and the smallest burden for acute hepatitis B. The study found that the main factors affecting the cost of disease were sex, age, occupational classification, place of residence, health insurance conditions, hospital class, length of hospitalization, use of antiviral drugs, comorbidities, and complications.

conclusionHepatitis B has caused a huge economic burden on Chinese society, and hidden costs also respond to a great psychological burden on patients and their families. Based on existing studies, there is an urgent need for high-quality, multicenter, population-level studies to inform clinical treatment and health policy decisions.

Indexed as

Direct costsEconomic burdenHepatitis BImplicit costsIndirect costsSystematic review Huanhuan Ye is the joint first author.

Identifiers

PMID39592510
PMCPMC11600740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.