ArticleAbdominal radiology (New York)2025
Pancreatic volume, fat content and T1 relaxation time using magnetic resonance imaging in patients with prior gestational diabetes mellitus.
Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the volume, fat content, and T1 relaxation time of the pancreas in participants with and without prior gestational diabetes mellitus (GDM).
methodsIn this prospective case-control study, we enrolled 29 women with prior GDM, and divided them into three groups (normoglycemic, prediabetic, and diabetic) based on their glycaemic status in the postpartum period; and a group of 13 participants as controls who had normoglycemia during pregnancy. Participants underwent MR examination including an axial multi-echo DIXON-based sequence and an axial-oblique T1 mapping sequence. The average proton density fat fraction (PDFF) and T1 value of the pancreas were measured by drawing multiple circular regions of interest (ROIs). Average hepatic PDFF was similarly calculated. Pancreatic volume was computed by summating cleaned freehand ROIs outlining pancreatic parenchyma.
resultsWomen were evaluated at a mean age of 32.9 ± 4.0 years and with a mean BMI of 25.2 ± 2.9 kg/m2. The median (IQR) duration of follow-up after childbirth was 24 (34-44) months. In controls, the pancreatic PDFF, T1 value, and volume were 5.4 ± 2.3%, 850.6 ± 101.6 ms, and 69.3 ± 16.2 cm³, respectively, while in subjects with a history of GDM, these values were 4.7 ± 2.0%, 844.6 ± 91.8 ms, and 69.8 ± 16.6 cm³, respectively. No statistical differences were observed (all p > 0.05). Mean hepatic PDFF was significantly higher in the diabetic and prediabetic groups (12.2 ± 6.4% and 11.0 ± 7.6% respectively) than in the control and normoglycemic groups (7.9 ± 7.3 and 4.7 ± 1.6% respectively; p -0.01).
conclusionWe did not find any significant changes in pancreatic volume, fat content, or fibrosis in women with prior GDM and with different glycaemic categories when evaluated in the early postpartum period, compared to the control group. These findings may be a consequence of the transient state of insulin resistance in GDM and the finite duration of the disease course in new-onset prediabetes and diabetes patients.
Indexed as
Identifiers
39592481What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.