Evidence map›Paper›PMID 39592477›Full record

SynthesisActa neurochirurgica2024

Lumbar Disc Herniation and Cauda Equina Syndrome During Pregnancy: A Systematic Review.

Amna Hussein, Esteban Quiceno, Niels Pacheco-Barrios, Nikhil Dholaria, Annemarie Pico, Giovanni Barbagli, James Kelbert, Diego T Soto-Rubio, Ibrahim A Alhalal, Abdullah K Al-Arfaj and 2 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Orthopedics in Pregnancy: Exploring Challenges and Solutions.Journal of pharmacy & bioallied sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amna HusseinDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA. amna.s.hussein@gmail.com.ORCID 0000-0002-4694-9989
Esteban QuicenoDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, USA.
Niels Pacheco-BarriosDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Nikhil DholariaDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Annemarie PicoDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Giovanni BarbagliDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
James KelbertDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Diego T Soto-RubioDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Ibrahim A AlhalalDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Abdullah K Al-ArfajDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Michael PrimDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.
Ali A BaajDepartment of Neurosurgery, Banner University Medical Center Phoenix USA- University of Arizona, 1111 E McDowell Rd, Phoenix, AZ, 85006, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow back pain is common during pregnancy, affecting up to 76% of women. However, symptomatic lumbar disc herniation (LDH) is rare, occurring in about 1 in 10,000 pregnancies, with less than 2% progressing to cauda equina syndrome (CES). The overlap in symptoms between LDH and typical pregnancy-related conditions complicates both diagnosis and management. This review aims to enhance understanding of LDH and CES during pregnancy and provide a comprehensive overview of treatment options. METHODOLOGY: A systematic review of the PubMed database was conducted following PRISMA guidelines, focusing on patient demographics, clinical presentation, diagnostics, treatment strategies, and outcomes.

resultsThirty-three case reports and series involving 51 pregnant women diagnosed with LDH and CES were analyzed. The average age was 33.2 years, with most symptoms occurring in the third trimester. Lower extremity pain (86.3%) and low back pain (78.4%) were the predominant symptoms, with 49.0% experiencing sphincter involvement. MRI was the primary diagnostic tool, identifying single-level disc herniation in 92.2% of cases. Antepartum spine surgery was performed on 74.5% of the women, predominantly through microdiscectomy, with 79.2% using general anesthesia. Post-surgery, 52.6% had cesarean sections, while 42.1% delivered vaginally. Adverse events were minimal (3.9%), and 62.7% of patients experienced favorable outcomes without neurological deterioration or maternal/fetal deaths.

conclusionAlthough rare, acute LDH and CES during pregnancy require prompt attention and intervention. MRI and emergent surgical treatment are generally safe and effective for both mother and fetus. Special surgical positioning and anesthesia management considerations are critical to minimizing risks and ensuring favorable outcomes.

Indexed as

Cauda Equina SyndromeIntervertebral Disc DisplacementLumbar VertebraePregnancy ComplicationsAdultDiskectomyFemaleHumansLow Back PainPregnancyAntepartum Spine SurgeryCauda Equina Syndrome (CES)Lumbar Disc Herniation (LDH)Maternal and Fetal OutcomesObstetric Neurological ComplicationsPregnancy-Related Spine Surgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.