Evidence map›Paper›PMID 39592290›Full record

ArticleClinical breast cancer2025

Perceptions of Delayed Alopecia Among Breast Cancer Survivors.

Sarah K Premji, Kathryn J Ruddy, Robert A Vierkant, Nicole Larson, Charles Loprinzi, Brittany Dulmage, Maryam Lustberg, Fergus J Couch, Janet E Olson, Elizabeth Cathcart-Rake

Abstract read
In one paragraph

Article in Clinical breast cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah K PremjiDivision of Medical Oncology, Mayo Clinic, Rochester, MN. Electronic address: Premji.Sarah@mayo.edu.
Kathryn J RuddyDivision of Medical Oncology, Mayo Clinic, Rochester, MN.
Robert A VierkantDepartment of Biostatistics, Mayo Clinic, Rochester, MN.
Nicole LarsonQuantitative Health Sciences, Mayo Clinic, Rochester, MN.
Charles LoprinziDivision of Medical Oncology, Mayo Clinic, Rochester, MN.
Brittany DulmageDepartment of Dermatology, Ohio State University, Columbus, OH.
Maryam LustbergDivision of Medical Oncology, Yale University, New Haven, CT.
Fergus J CouchDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Janet E OlsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.
Elizabeth Cathcart-RakeDivision of Medical Oncology, Mayo Clinic, Rochester, MN.

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mayo Clinic Building Interdisciplinary Research Careers in Women’s HealthK12AR084222 · NIAMS · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2023 to 2024
$733k
Screening Mammography: Early Breast Cancer Detection for All at RiskK23MD019644 · NIMHD · MAYO CLINIC ROCHESTER · PI Elizabeth Cathcart-Rake · 2024 to 2026
$467k
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA015083NIAMS NIH HHS K12 AR084222NIMHD NIH HHS K23 MD019644
6 · The paper itself

Abstract

backgroundRetrospective studies suggest that some breast cancer survivors report treatment-associated hair loss or thinning years after their diagnosis. This study investigates frequency and perceptions of alopecia persisting 6 years after patients' breast cancer diagnoses.

methodsBreast cancer survivors participating in the Mayo Clinic Breast Disease Registry (MCBDR) were mailed a survey 6 years after diagnosis. They were asked about their degree of bother from hair thinning and hair loss and mental health was explored.

resultsA total of 969 of 1476 participants (65.7%) responded to the survey. Of these, 755 patients were eligible for inclusion and had stage I-III breast cancer. Respondents' median age was 65.6 years (35-95 years). Chemotherapy (± endocrine therapy) was administered to 216 (29%) participants, and 342 (45%) received only endocrine therapy. Nearly half (345, 46%) of respondents reported hair loss and over half (431, 57%) reported hair thinning. Moderate to extreme bother from hair loss was reported by 27% of chemotherapy recipients, by 18% of endocrine therapy only recipients, and by 14% of patients who received neither. Moderate to extreme bother from hair thinning was reported by 31% of chemotherapy recipients, by 21% of endocrine therapy-only recipients, and by 19% of those who had received neither. Hair growth product usage was reported by 31% of chemotherapy recipients and 14% of endocrine therapy-only recipients.

conclusionsHair loss and thinning are frequently reported as persistently bothersome symptoms by breast cancer survivors. Future investigations into the incidence, predictors, and treatment of therapy-associated alopecia are needed.

Indexed as

AlopeciaBreast NeoplasmsCancer SurvivorsAdultAgedAged, 80 and overFemaleHumansMiddle AgedPerceptionRetrospective StudiesSurveys and QuestionnairesBreast cancer treatmentChemotherapyEndocrine therapy alopeciaHair re-growthMental health

Identifiers

PMID39592290
PMCPMC11769767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.