Evidence map›Paper›PMID 39591546›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2025

Randomized Controlled Trial of a Virtually Delivered Exercise and Stress Management Program to Improve Physical Performance of Hematopoietic Cell Transplant Survivors.

David D Ma, Zhixin Liu, Kimberley Au, Mei Tran, Crisbel M Artuz, Matthew Greenwood, Ian Bilmon, David Kliman

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David D MaSt Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.ORCID 0009-0004-0242-5181
Zhixin LiuStats Central, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia.
Kimberley AuSt Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.ORCID 0000-0002-3782-2628
Mei TranSt Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.ORCID 0000-0002-9163-5831
Crisbel M ArtuzClinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia.ORCID 0009-0005-8475-1972
Matthew GreenwoodRoyal North Shore Hospital, St Leonards, NSW, Australia.ORCID 0000-0002-3667-2613
Ian BilmonUniversity of Sydney, Sydney, NSW, Australia.
David KlimanSt Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.ORCID 0000-0002-2020-0275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBecause of advances in hematopoietic cell transplant (HCT), meeting the long-term health needs of increasing numbers of HCT survivors remains challenging. This multicenter trial aimed to assess the short- and long-term effects of an exercise and mindfulness intervention delivered by telehealth.

methodsOne hundred thirty-nine participants >6 months post-HCT were randomly assigned 1:1 to a 6-week personalized exercise and mindfulness training with three motivation sessions at 3-6 months via an online meeting platform or usual care. Physical and quality-of-life (QOL) assessments were conducted online for 12 months. The primary end point was the 6-minute walk test (6-MWT) at 3 months.

resultsThe median time post-HCT was 21 months (range, 7-67 months). Improvement in mean difference of 6-MWT was found in the intervention group compared with control (intention-to-treat) at 3 months (51.4 m [95% CI, 27.3 to 75.5];

conclusionThe supervised multimodal telehealth intervention provided clinically meaningful and durable improvement of physical capacity in HCT survivors. This home-based program has the potential to provide an unmet need for HCT survivors. Similar programs may benefit survivors of other cancers, organ transplants, and chronic disorders.

Indexed as

ExerciseExercise TherapyHematopoietic Stem Cell TransplantationMindfulnessPhysical Functional PerformanceStress, PsychologicalSurvivorsAdultAgedFemaleHumansMaleMiddle AgedQuality of LifeTelemedicine

Identifiers

PMID39591546
PMCPMC11895824

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.