Evidence map›Paper›PMID 39591522›Full record

ReviewChemical reviews2024

Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis.

Lauren E Ehehalt, Omar M Beleh, Isabella C Priest, Julianna M Mouat, Alyssa K Olszewski, Benjamin N Ahern, Alexandro R Cruz, Benjamin K Chi, Anthony J Castro, Kai Kang and 2 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Base-Free C-N Cross-Electrophile Coupling.Journal of the American Chemical Society · 2026
    Article
  8. Ligand-Enabled Stereoselective Coupling of Methylene C(spAngewandte Chemie (International ed. in English) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. A Ni-Mediated Cross-Coupling Approach to DeuteratedJournal of the American Chemical Society · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lauren E EhehaltDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0003-4267-214X
Omar M BelehDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0001-8927-5382
Isabella C PriestDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-3265-6907
Julianna M MouatDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-3976-3676
Alyssa K OlszewskiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-3707-5423
Benjamin N AhernDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Alexandro R CruzDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0003-2296-3329
Benjamin K ChiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0001-5672-9827
Anthony J CastroDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Kai KangDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Jiang WangDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Daniel J WeixDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-9552-3378

Funding

Reductive Coupling Reactions: Trading Organometallic Reagents for Organic HalidesR01GM097243 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Daniel John Weix · 2011 to 2026
$5.6M
Chemistry-Biology Interface Training ProgramT32GM152341 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Helen E. Blackwell · 2024 to 2026
$1.6M
Nickel Cross-Coupling Cascades with α-Heteroatom Radicals to Prepare Sterically Hindered Alcohols and AminesF32GM146357 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BELEH, OMAR · 2023 to 2025
$160k
NIGMS NIH HHS F32 GM146357NIGMS NIH HHS R01 GM097243NIGMS NIH HHS T32 GM152341
6 · The paper itself

Abstract

Cross-electrophile coupling (XEC), defined by us as the cross-coupling of two different σ-electrophiles that is driven by catalyst reduction, has seen rapid progression in recent years. As such, this review aims to summarize the field from its beginnings up until mid-2023 and to provide comprehensive coverage on synthetic methods and current state of mechanistic understanding. Chapters are split by type of bond formed, which include C(sp

Identifiers

PMID39591522
PMCPMC11638928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.