Evidence map›Paper›PMID 39591322›Full record

ArticleVeterinary sciences2024

Whole-Genome Analysis of Porcine Epidemic Diarrhea Virus from Yunnan, China.

Runting Zhang, Gefen Yin, Yunhua Wang, Yongneng Li, Xinxian Wang, Junlong Bi, Guishu Yang, Kaixing Qu, Libo Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Runting ZhangCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Gefen YinCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Yunhua WangCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Yongneng LiCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Xinxian WangCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Junlong BiCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Guishu YangCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.
Kaixing QuAcademy of Science and Technology, Chuxiong Normal University, Chuxiong 675000, China.
Libo GaoCollege of Animal Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China.ORCID 0009-0001-3585-7288

Funding

Yunnan Provincial Innovation Team of Key Technologies for Prevention and Control of Important Livestock and Poultry Diseases 202405AS350004
6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is a member of the genus α-coronavirus and causes severe diarrhea in piglets, leading to enormous economic losses in the pig industry. To understand the epidemic variation of PEDV strains in Yunnan province, three PEDV strains (YN2021, YNLP 2022, and YNBS 2022) and one commercially available attenuated vaccine strain (Attenuated AJ1102-R) that were previously isolated were sequenced and compared with the representative PEDV strains. NJ phylogenetic analysis showed that YN2021 strain and Attenuated CV777 strain were clustered into GI-b subtype, while YNLP 2022 and YNBS 2022 belong to GII-b subtype, accompanying ZJCZ4 and Attenuated AJ1102-R. RDP analysis revealed that YNLP 2022 was a genome recombination from both GII-b strain PEDV-7C and GII-a strain YN1, of which the recombination region is in the range nt4994-7605. YNBS 2022 strain was another recombination originated from GII-b subtype strain 17GXZC-1ORF3c and GII-a subtype strain PEDV-CHZ, of which the counterpart is in the range nt16399-22326. The Yunnan strain of PEDV was analyzed for the first time from the whole-genome perspective, and comprehensive analysis showed that the Yunnan strains have high genetic variation. This study may shed new light on the current PEDV infections in Yunnan and pave the way toward further control of PEDV infections.

Indexed as

genetic variationgenome recombinationphylogenetic analysisporcine epidemic diarrhea virusYunnan province

Identifiers

PMID39591322
PMCPMC11599152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.