ReviewVeterinary sciences2024
Pharmacokinetics of Meloxicam in Different Animal Species: A Comprehensive Review.
Review in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Antimicrobial Use in Dromedary Camels: Off-Label Practices, Welfare Implications, and Antimicrobial Resistance Within a One Health Framework-A Narrative Review.Veterinary sciences · 2026Review
- Triple-layered core-shell microneedle patch for sustained analgesic delivery and chondroprotection in osteoarthritis.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- The Potential of Selective COX-2 Inhibitor Mavacoxib for Extended Analgesia in Sheep Husbandry.Animals : an open access journal from MDPI · 2026Article
- Article
- Review
- Pharmacokinetics and Bioavailability of Tolfenamic Acid in Calves: First Evaluation of Subcutaneous Administration.Veterinary medicine and science · 2026Article
- Meloxicam blood levels are not affected by sex-related hormones in male and female goats.Veterinarni medicina · 2026Article
- Pharmacokinetic Parameters of Oral Firocoxib, Oral Meloxicam, and Transdermal Flunixin in Meat Type Goats.Journal of veterinary pharmacology and therapeutics · 2026Article
- Temperature-responsive hydrogel of oclacitinib maleate administered via the rectum in rabbit.Frontiers in veterinary science · 2026Article
- Analgesic combinations to reduce the stress/pain responses in ewes submitted to non-surgical embryo recovery: butorphanol associated with meloxicam or with dipyrone/hyoscine.Animal reproduction · 2026Article
- Draft genome sequence of the meloxicam-degradingMicrobiology resource announcements · 2025Article
- Effect of Gender on the Pharmacokinetics of Meloxicam in Sheep.Journal of veterinary pharmacology and therapeutics · 2025Article
- Fungal mediated production of novel metabolites of meloxicam and their tankyrase-2 inhibition potentials: an in silico study.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Effect of Meloxicam on the Pharmacokinetics of Cefquinome in Endotoxemic Sheep.Veterinary medicine and science · 2025Article
- Comparison of Intravenous and Oral Meloxicam Pharmacokinetics in Female and Male Saanen Goats.Veterinary sciences · 2025Article
- New Gel Approaches for the Transdermal Delivery of Meloxicam.Gels (Basel, Switzerland) · 2025Review
- The Evaluation of Potential Anticancer Activity of Meloxicam-In Vitro Study on Amelanotic and Melanotic Melanoma.International journal of molecular sciences · 2025Article
- Meloxicam Alleviates Oxidative Stress Through Nrf2/HO-1 Activation in Bovine Endometrial Epithelial Cells.Veterinary sciences · 2025Article
- Plasma pharmacokinetics, milk residue depletion profile, and milk withdrawal interval estimation following multiple-dose oral administration of meloxicam to lactating dairy goats.Frontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meloxicam is a non-steroidal anti-inflammatory in the oxicam group. It has been extensively used in human and veterinary medicine for their anti-inflammatory, analgesic and antipyretic activities. Meloxicam has shown high therapeutic potential for disorders such as osteoarthritis, musculoskeletal disorder, acute respiratory infection, puerperal septicemia, mastitis and mastitis-metritis-agalactia syndrome. Although meloxicam pharmacokinetic has been described for numerous species, no paper summarizes the existing literature on this field. Thus, the aim of this review was to carry out a review of the literature on the pharmacokinetics of meloxicam in different animal species and gather the data in a single review article. A comprehensive review of the available literature in the PubMed, Web of Science and Scopus databases was performed. Meloxicam shows good bioavailability after oral and parenteral administration in most animal species (85-95%), with the lowest values in sheep after oral administration. It presents a rapid distribution with a small volume of distribution, which can be attributed to relatively high ionization state of meloxicam at physiological pH and its high plasma protein binding (close to 99%). It is extensively metabolized in the liver in several inactive polar metabolites, which are excreted, like unchanged meloxicam in urine and feces. Meloxicam also shows a long elimination half-life and low clearance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.