Evidence map›Paper›PMID 39591276›Full record

ArticleTropical medicine and infectious disease2024

Polymorphisms in the ACE I/D (

Yan Cardoso Pimenta, Flávia Freitas de Oliveira Bonfim, Carlos Eduardo da Silva Figueiredo, Bruno Loreto de Aragão Pedroso, Mauro França Silva, Alberto Ignacio Olivares Olivares, Isabella Fernandes Delgado, José Paulo Gagliardi Leite, Marcia Terezinha Baroni de Moraes

Abstract read
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In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan Cardoso PimentaLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0002-5000-9842
Flávia Freitas de Oliveira BonfimLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0003-2816-5176
Carlos Eduardo da Silva FigueiredoLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.
Bruno Loreto de Aragão PedrosoLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.
Mauro França SilvaLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.
Alberto Ignacio Olivares OlivaresSecretaria Estadual de Saúde de Roraima, SESAU/RR, Rua Madrid, 180-Aeroporto, Boa Vista 69310-043, RR, Brazil.
Isabella Fernandes DelgadoPost-Graduate Program in Sanitary Surveillance, National Institute for Quality Control in Health, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.
José Paulo Gagliardi LeiteLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.
Marcia Terezinha Baroni de MoraesLaboratory of Comparative and Environmental Virology, Oswald °Cruz Institute, Oswald °Cruz Foundation, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-360, RJ, Brazil.

Funding

CAPES 88887.977276/2024-00CNPQ 408463/2022-8Faperj E26/210.057/2020 and E26/210.701/2024
6 · The paper itself

Abstract

COVID-19 infection caused by SARS-CoV-2 continues to cause significant mortality and morbidity. ACE2 is a key regulator of the renin-angiotensin-aldosterone system (RAAS). Differences in COVID-19 severity are thought to be due to the imbalance of RAAS/ACE mutations. This retrospective study evaluated the detection and genetic susceptibility to SARS-CoV-2 infection in 202 children ≤3 years of age living in the Amazon region in 2021. The angiotensin-converting enzyme ACE I/D (

Indexed as

angiotensin-converting enzymeCOVID-19SARS-CoV-2susceptibility

Identifiers

PMID39591276
PMCPMC11598624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.