Evidence map›Paper›PMID 39591253›Full record

ArticleToxins2024

Comparative Assessment of the Allergenicity of Hyaluronidases from

Johannes Grosch, Bernadette Eberlein, Sebastian Waldherr, Mariona Pascal, Britta Dorn, Clara San Bartolomé, Federico De La Roca Pinzón, Maximilian Schiener, Ulf Darsow, Tilo Biedermann and 5 more

Abstract readComparative Study
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Homology Analysis ofToxins · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Johannes GroschCenter of Allergy and Environment (ZAUM), Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, 85764 Munich, Germany.
Bernadette EberleinDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, 80802 Munich, Germany.ORCID 0000-0003-4509-6491
Sebastian WaldherrDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, 80802 Munich, Germany.
Mariona PascalImmunology Department, CDB Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0003-0549-9720
Britta DornExperimental Dermatology and Allergy Research Group, Department of Dermatology and Allergology, Justus-Liebig-University Gießen, 35392 Gießen, Germany.ORCID 0009-0000-8210-3422
Clara San BartoloméImmunology Department, CDB Hospital Clinic de Barcelona, Universitat de Barcelona, 08007 Barcelona, Spain.
Federico De La Roca PinzónAllergy Section, Hospital Clinic de Barcelona, Clinical Medical Group, 08036 Barcelona, Spain.
Maximilian SchienerCenter of Allergy and Environment (ZAUM), Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, 85764 Munich, Germany.
Ulf DarsowDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, 80802 Munich, Germany.
Tilo BiedermannDepartment of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich, 80802 Munich, Germany.ORCID 0000-0002-5352-5105
Jonas LidholmThermo Fisher Scientific, 75450 Uppsala, Sweden.ORCID 0000-0002-7779-3411
Maria Beatrice BilòDepartment of Clinical and Molecular Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.
Thilo JakobExperimental Dermatology and Allergy Research Group, Department of Dermatology and Allergology, Justus-Liebig-University Gießen, 35392 Gießen, Germany.ORCID 0000-0002-3124-9998
Carsten B Schmidt-WeberCenter of Allergy and Environment (ZAUM), Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, 85764 Munich, Germany.ORCID 0000-0002-3203-8084
Simon BlankCenter of Allergy and Environment (ZAUM), Technical University of Munich, School of Medicine and Health & Helmholtz Munich, German Research Center for Environmental Health, 85764 Munich, Germany.ORCID 0000-0002-5649-1078

Funding

Helmholtz Association ZT-0027
6 · The paper itself

Abstract

Sensitization to cross-reactive allergens complicates identifying the culprit insect in Hymenoptera venom allergy via diagnostic tests. This study evaluates sensitization to hyaluronidases (Api m 2 from honey bee (

Indexed as

AllergensBee VenomsCross ReactionsWasp VenomsAdolescentAdultAgedAnimalsBeesChildFemaleHumansHypersensitivityImmunoglobulin EInsect Bites and StingsInsect ProteinsAllergensBee VenomsImmunoglobulin EInsect ProteinsWasp Venomsallergen cross-reactivityApi m 2Apis melliferahyaluronidasesHymenoptera venom allergyPol d 2Polistes dominulaVespula vulgarisVes v 2

Identifiers

PMID39591253
PMCPMC11598713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.