Evidence map›Paper›PMID 39591238›Full record

ReviewToxins2024

Dietary Mycotoxins: An Overview on Toxicokinetics, Toxicodynamics, Toxicity, Epidemiology, Detection, and Their Mitigation with Special Emphasis on Aflatoxicosis in Humans and Animals.

James Kibugu, Leonard Munga, David Mburu, Fredrick Maloba, Joanna E Auma, Delia Grace, Johanna F Lindahl

Abstract readReview
In one paragraph

Review in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Aflatoxin exposure and health impacts: global burden and advances in detection technologies.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Effect of environmental contamination on male and female gametes.The Journal of reproduction and development · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Green-Synthesized Nanomaterials for Aflatoxin Mitigation: A Review.Nanotechnology, science and applications · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James KibuguBiotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, P.O. Box 362, Kikuyu 00902, Kenya.ORCID 0000-0002-5764-5083
Leonard MungaDepartment of Animal Science, School of Agriculture and Environmental Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya.ORCID 0000-0003-2724-4868
David MburuDepartment of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya.ORCID 0000-0002-0102-6291
Fredrick MalobaDepartment of Zoological Sciences, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya.
Joanna E AumaBiotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, P.O. Box 362, Kikuyu 00902, Kenya.ORCID 0000-0002-0717-5554
Delia GraceDepartment of Biosciences, International Livestock Research Institute, P.O. Box 30709, Nairobi 00100, Kenya.ORCID 0000-0002-0195-9489
Johanna F LindahlDepartment of Animal Health and Antibiotic Strategies, Swedish Veterinary Agency, 75189 Uppsala, Sweden.ORCID 0000-0002-1175-0398

Funding

Consultative Group on International Agricultural Research (CGIAR) CRA between ILRI and KALRO Ref. Contract No. 1/2014
6 · The paper itself

Abstract

Mycotoxins are secondary metabolites of filamentous fungi and ubiquitous dietary contaminants. Aflatoxins, a group of mycotoxins with high prevalence and toxicity, have raised a high level of public health concern, the most prevalent and toxic being aflatoxin B1 (AFB1). Many aspects appertaining to AFB1 poisoning are not well understood. Yet this information is necessary to devise appropriate surveillance and mitigation strategies against human and animal aflatoxicosis. This review provides an in-depth update of work carried out on mycotoxin poisoning, particularly aflatoxicosis in humans and animals, to identify gaps in knowledge. Hypotheses explaining the functional significance of mycotoxins in fungal biology and their dietary epidemiological data are presented and briefly discussed. The toxicology of aflatoxins and the challenges of their mitigation are discussed in depth. It was concluded that the identification of potential mycotoxin-hazard-prone food items and quantification of the associated risk of cancer ailments in humans is a prime priority. There is a dearth of reliable sampling methodologies for estimating AFB1 in animal feed. Data update on AFB1 in animal feed and its implication in animal production, mitigation strategies, and elucidation of risk factors to this hazard is required. To reduce the burden of aflatoxins, surveillance employing predictive technology, and biocontrol strategies seem promising approaches.

Indexed as

Animal FeedFood ContaminationAflatoxin B1Aflatoxin PoisoningAflatoxinsAnimalsDietHumansMycotoxicosisMycotoxinsToxicokineticsAflatoxin B1AflatoxinsMycotoxinsaflatoxincontrol strategiesdetectionepidemiologymycotoxinstoxicitytoxicology

Identifiers

PMID39591238
PMCPMC11598113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.