Evidence map›Paper›PMID 39591195›Full record

ReviewVaccines2024

Human Papillomavirus (HPV) Vaccination: Progress, Challenges, and Future Directions in Global Immunization Strategies.

Francesco Branda, Grazia Pavia, Alessandra Ciccozzi, Angela Quirino, Nadia Marascio, Simona Gigliotti, Giovanni Matera, Chiara Romano, Chiara Locci, Ilenia Azzena and 6 more

Abstract readReview
In one paragraph

Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Cancer mortality predictions for 2026 in selected Asian countries and Australia with focus on prostate cancer.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
    Article
  4. Review
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  7. Article
  8. Article
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  11. Review
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  14. Mouse Papillomavirus Outbreak in a Research Facility.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Francesco BrandaUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-9485-3877
Grazia PaviaUnit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University of Catanzaro-"Renato Dulbecco" Teaching Hospital, 88100 Catanzaro, Italy.ORCID 0000-0002-7685-3419
Alessandra CiccozziDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Angela QuirinoUnit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University of Catanzaro-"Renato Dulbecco" Teaching Hospital, 88100 Catanzaro, Italy.
Nadia MarascioUnit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University of Catanzaro-"Renato Dulbecco" Teaching Hospital, 88100 Catanzaro, Italy.ORCID 0000-0003-0880-8955
Simona GigliottiUnit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University of Catanzaro-"Renato Dulbecco" Teaching Hospital, 88100 Catanzaro, Italy.
Giovanni MateraUnit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University of Catanzaro-"Renato Dulbecco" Teaching Hospital, 88100 Catanzaro, Italy.
Chiara RomanoUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Chiara LocciDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Ilenia AzzenaDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Noemi PascaleDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Daria SannaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3058-4663
Marco CasuDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-5042-4851
Giancarlo CeccarelliDepartment of Public Health and Infectious Diseases, University Hospital Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-5921-3180
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0003-3866-9239
Fabio ScarpaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) is a widespread viral pathogen, responsible for a significant burden of cervical and other cancers worldwide. Over the past decades, the development and widespread adoption of prophylactic HPV vaccines have dramatically reduced the incidence of HPV-related diseases. However, despite the efficacy of these vaccines, global immunization efforts still face several obstacles, including low vaccination coverage in low- and middle-income countries, vaccine hesitancy, and disparities in access to healthcare. This review aims to provide a comprehensive overview of the current state of HPV vaccines, including their mechanisms of action, safety profiles, and real-world efficacy. We will explore the impact of HPV vaccines on cancer prevention, examine the challenges related to vaccine distribution and uptake, and assess the role of public health policies in improving global vaccination rates. Additionally, the review will highlight the latest advancements in therapeutic HPV vaccines, ongoing research into next-generation vaccines, and the potential of HPV vaccination strategies in the context of personalized medicine. By examining these factors, we aim to provide insights into the future directions of HPV vaccination and its role in global public health.

Indexed as

cancer preventionglobal immunization strategiesHPV vaccinationhuman papillomavirus (HPV)next-generation vaccinespersonalized medicine in vaccinationpublic health policyvaccine hesitancy

Identifiers

PMID39591195
PMCPMC11598998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.