Evidence map›Paper›PMID 39591105›Full record

ArticleVaccines2024

Invasive Pneumococcal Diseases in People over 65 in Veneto Region Surveillance.

Silvia Cocchio, Claudia Cozzolino, Andrea Cozza, Patrizia Furlan, Irene Amoruso, Francesca Zanella, Filippo Da Re, Debora Ballarin, Gloria Pagin, Davide Gentili and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Journal of preventive medicine and hygiene · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Silvia CocchioDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0003-3801-0901
Claudia CozzolinoDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0001-7628-9515
Andrea CozzaDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0001-9156-9312
Patrizia FurlanDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.
Irene AmorusoDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0003-4954-5848
Francesca ZanellaRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.
Filippo Da ReRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.ORCID 0009-0006-7366-0108
Debora BallarinRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.
Gloria PaginRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.
Davide GentiliRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.ORCID 0000-0002-7852-191X
Michele TononRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.ORCID 0000-0002-4917-404X
Francesca RussoRegional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy.
Tatjana BaldovinDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0002-7375-9187
Vincenzo BaldoDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0001-6012-9453

Funding

Veneto Regional Authority
6 · The paper itself

Abstract

backgroundElderly individuals over 65, along with children under 5, are the most affected by invasive pneumococcal diseases (IPDs). Monitoring vaccination coverage and conducting surveillance are essential for guiding evidence-based prevention campaigns and public health measures.

methodsSince 2007, the Veneto Region has relied on three sources for surveillance of invasive bacterial infections, contributing to an increase in reported IPD cases. This study analyzed notifications related to individuals aged ≥65 years from 2007 to 2023.

resultsA total of 1527 cases of IPDs in elderly individuals were reported between 2007 and 2023. The notification rate significantly increased from 5.61 to 14.63 per 100,000 inhabitants, despite underreporting during the COVID-19 pandemic. Cases associated with sepsis increased from 3.89 to 9.58 per 100,000, while notifications of meningitis and case fatality rates remained stable at 1.5 per 100,000 and 11.8%, respectively. Serotyping was not performed in 52% of the notifications. The most common serotypes were 3 (21.6%), 8 (11.1%), and 19A (5.0%), with fluctuations over time. There was a significant decline in serotypes covered by PCV7 and PCV13 and an increase in non-vaccine serotypes.

conclusionsThe regional surveillance system allows for an increasingly comprehensive profile of the epidemiological landscape of IPDs in Veneto. However, the surveillance of pneumococcal infections still presents challenges. The currently available data are likely to be underestimated, mainly referring to the most severe cases, and the serotyping necessary to identify the etiological agent is still not often performed.

Indexed as

elderlyinvasive bacterial diseasespneumococcal vaccinationStreptococcus pneumoniaesurveillance

Identifiers

PMID39591105
PMCPMC11598215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.