Evidence map›Paper›PMID 39591000›Full record

ArticleToxics2024

Effects of Co-Exposure to Benzene, Toluene, and Xylene, Polymorphisms of microRNA Genes, and Their Interactions on Genetic Damage in Chinese Petrochemical Workers.

Shuangqi Li, Xiaojing Liao, Rui Ma, Na Deng, Haimei Wu, Zhaorui Zhang, Liping Chen, Qing Wang, Qilong Liao, Qianxi Li and 3 more

Abstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shuangqi LiDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.ORCID 0009-0007-1972-7743
Xiaojing LiaoSchool of Public Health, Guangzhou Medical University, Xinzao Road, Panyu District, Guangzhou 511436, China.
Rui MaDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Na DengDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Haimei WuDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Zhaorui ZhangSchool of Public Health, Guangzhou Medical University, Xinzao Road, Panyu District, Guangzhou 511436, China.
Liping ChenDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Qing WangDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Qilong LiaoDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Qianxi LiSchool of Public Health, Guangzhou Medical University, Xinzao Road, Panyu District, Guangzhou 511436, China.
Xinyi OuyangSchool of Public Health, Guangzhou Medical University, Xinzao Road, Panyu District, Guangzhou 511436, China.
Yongmei XiaoDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2nd Road, Yuexiu District, Guangzhou 510080, China.
Qifei DengSchool of Public Health, Guangzhou Medical University, Xinzao Road, Panyu District, Guangzhou 511436, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2020A1515010753Guangdong Basic and Applied Basic Research Foundation 2024A1515012072Guangdong Basic and Applied Basic Research Foundation 2024A1515030225National Natural Scientific Foundation of China 81402658National Natural Scientific Foundation of China 81973006National Natural Scientific Foundation of China 81973076Science and Technology Planning Project of Guangzhou 202002030281Young Teachers Training Program of Sun Yat-sen University 18ykpy14
6 · The paper itself

Abstract

Benzene, toluene, and xylene (BTX) co-exist in human environments, yet their individual and combined effects on genetic damage at low exposure levels are not fully understood. Additionally, single nucleotide polymorphisms in microRNAs (mirSNPs) might be involved in cancer etiology by affecting the related early health damage. To investigate the influence of BTX exposure, mirSNPs, and their interactions on genetic damage, we conducted a cross-sectional study in 1083 Chinese petrochemical workers, quantifying the BTX cumulative exposure levels and multiple genetic damage biomarkers. Additionally, we genotyped multiple common mirSNPs. Benzene and a BTX mixture were positive associated with the olive tail moment (OTM) and tail DNA% (

Indexed as

BTX co-exposuregene–environment interactiongenetic damagegenetic polymorphismsmicroRNApetrochemical workers

Identifiers

PMID39591000
PMCPMC11598265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.