Evidence map›Paper›PMID 39590774›Full record

ArticleMarine drugs2024

Design, Synthesis, and Evaluation of Novel Thiazole-Containing Algicides Inspired by Bacillamide A.

Xiaoxue Li, Huili Li, Lei Shi, Zuguang Yin, Yuguo Du, Hongxia Zhang, Xin Wang, Xinxin Wang, Kexin Xu, Weili Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoxue LiSchool of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.
Huili LiSchool of Life Sciences, Yantai University, Yantai 264005, China.
Lei ShiSchool of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.
Zuguang YinSchool of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.
Yuguo DuState Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Hongxia ZhangSchool of Life Sciences, Yantai University, Yantai 264005, China.
Xin WangSchool of Life Sciences, Yantai University, Yantai 264005, China.
Xinxin WangSchool of Life Sciences, Yantai University, Yantai 264005, China.
Kexin XuSchool of Life Sciences, Yantai University, Yantai 264005, China.
Weili WangSchool of Chemistry and Material Science, Ludong University, 186 Hongqi Middle Road, Yantai 264025, China.
Ronglian XingSchool of Life Sciences, Yantai University, Yantai 264005, China.
Yi LiuSchool of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.ORCID 0000-0003-1513-8638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pursuit of highly effective, low-toxicity, and eco-friendly algicides for controlling and eradicating harmful algal blooms (HABs) is of paramount importance. The natural allelochemical bacillamide A has displayed impressive algicidal activity against harmful algae with favorable safety profiles. However, the poor synthetic efficiency and large dose requirements of bacillamide A limit its further application. In this paper, 17 thiazole-containing bacillamide derivatives (BDs) were designed and synthesized in three linear steps as potential algicides. Eight compounds (

Indexed as

Drug DesignHarmful Algal BloomThiazolesDinoflagellidaStructure-Activity RelationshipThiazolesalgicidal activityallelopathic algicideBacillamide Aharmful algal bloomsSARthiazole-containing derivatives

Identifiers

PMID39590774
PMCPMC11595864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.