Evidence map›Paper›PMID 39590763›Full record

ArticleMarine drugs2024

Direct Preparation of Alginate Oligosaccharides from Brown Algae by an Algae-Decomposing Alginate Lyase AlyP18 from the Marine Bacterium

Xiao-Hui Sun, Xiao-Dong Zhang, Xin-Ru Zhang, Xiao-Fei Wang, Xi-Ying Zhang, Yu-Zhong Zhang, Yu-Qiang Zhang, Fei Xu

Abstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Hui SunState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Xiao-Dong ZhangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Xin-Ru ZhangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Xiao-Fei WangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Xi-Ying ZhangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Yu-Zhong ZhangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.ORCID 0000-0002-2017-1005
Yu-Qiang ZhangState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Fei XuState Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.ORCID 0000-0001-8541-199X

Funding

Marine S&T Fund of Shandong Province for Qingdao Marine Science and Technology Center No.2022QNLM030004-3National Science Foundation of China 32270047National Science Foundation of China 32330001National Science Foundation of China 42076151National Science Foundation of China U2006205
6 · The paper itself

Abstract

Alginate oligosaccharides (AOs), derived from alginate degradation, exhibit diverse biological activities and hold significant promise in various fields. The enzymatic preparation of AOs relies on alginate lyases, which offers distinct advantages. In contrast to the conventional use of sodium alginate derived from brown algae as the substrate for the enzymatic preparation of AOs, AO preparation directly from brown algae is more appealing due to its time and energy efficiency. Thus, the identification of potent alginate lyases and cost-effective brown algae substrates is crucial for optimizing AO production. Herein, we identified and characterized an alginate lyase, AlyP18, capable of efficiently decomposing algae, from a marine bacterium

Indexed as

AlginatesOligosaccharidesPhaeophyceaePolysaccharide-LyasesPseudoalteromonasAquatic OrganismsBacterial ProteinsHydrolysisLaminariaMacrocystisAlginatesBacterial ProteinsOligosaccharidespoly(beta-D-mannuronate) lyasePolysaccharide-Lyasesalginate lyasealginate oligosaccharidesbrown algaeLaminaria japonicaMacrocystis pyrifera

Identifiers

PMID39590763
PMCPMC11595925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.