Evidence map›Paper›PMID 39590759›Full record

ArticleJournal of imaging2024

AQSA-Algorithm for Automatic Quantification of Spheres Derived from Cancer Cells in Microfluidic Devices.

Ana Belén Peñaherrera-Pazmiño, Ramiro Fernando Isa-Jara, Elsa Hincapié-Arias, Silvia Gómez, Denise Belgorosky, Eduardo Imanol Agüero, Matías Tellado, Ana María Eiján, Betiana Lerner, Maximiliano Pérez

Abstract read
In one paragraph

Article in Journal of imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Belén Peñaherrera-PazmiñoCentro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador.ORCID 0000-0002-3886-7297
Ramiro Fernando Isa-JaraSpecial Coatings and Nanostructures Engineering (IREN), National Technological University, Buenos Aires 1706, Argentina.ORCID 0000-0001-5624-5822
Elsa Hincapié-AriasFacultad de Medicina, Universidad de Buenos Aires, Instituto de Oncología Ángel H. Roffo, Buenos Aires C1417, Argentina.ORCID 0009-0000-1911-3505
Silvia GómezFacultad de Medicina, Universidad de Buenos Aires, Instituto de Oncología Ángel H. Roffo, Buenos Aires C1417, Argentina.
Denise BelgoroskyFacultad de Medicina, Universidad de Buenos Aires, Instituto de Oncología Ángel H. Roffo, Buenos Aires C1417, Argentina.
Eduardo Imanol AgüeroFacultad de Medicina, Universidad de Buenos Aires, Instituto de Oncología Ángel H. Roffo, Buenos Aires C1417, Argentina.
Matías TelladoVetOncologia Cancer Clinic Buenos Aires, Buenos Aires C1408, Argentina.
Ana María EijánFacultad de Medicina, Universidad de Buenos Aires, Instituto de Oncología Ángel H. Roffo, Buenos Aires C1417, Argentina.
Betiana LernerSpecial Coatings and Nanostructures Engineering (IREN), National Technological University, Buenos Aires 1706, Argentina.ORCID 0000-0003-3341-5686
Maximiliano PérezSpecial Coatings and Nanostructures Engineering (IREN), National Technological University, Buenos Aires 1706, Argentina.

Funding

CATECHOLAMINES AND REPRODUCTIVE AGINGR01AG002021 · NIA · UNIVERSITY OF FLORIDA · PI SIMPKINS, JAMES W. · 1985 to 1990
–
Agencia de Promoción Cientifica y Tecnologica PICT 2018-02804, PICT-2017-0776, PICT START-UP-2020-00017National Scientific and Technical Research Argentinian Council (CONICET) and National Agency for the Promotion of Research, Technological Development and Innovation PICT 2021-00058, PICT 2021 GRF-00464, PICT 2021-00167, PICT 2020 SERIEA-01571, PICT STARTUP 2020-0017, PICT 2021-00124Universidad de Buenos Aires, UBACyT 20720190100005BA
6 · The paper itself

Abstract

Sphere formation assay is an accepted cancer stem cell (CSC) enrichment method. CSCs play a crucial role in chemoresistance and cancer recurrence. Therefore, CSC growth is studied in plates and microdevices to develop prediction chemotherapy assays in cancer. As counting spheres cultured in devices is laborious, time-consuming, and operator-dependent, a computational program called the Automatic Quantification of Spheres Algorithm (ASQA) that detects, identifies, counts, and measures spheres automatically was developed. The algorithm and manual counts were compared, and there was no statistically significant difference (

Indexed as

algorithmartificial intelligencecancerCSCsmicrofluidicsprediction

Identifiers

PMID39590759
PMCPMC11595607

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.