Evidence map›Paper›PMID 39590541›Full record

ArticleJournal of functional biomaterials2024

Enhancing the Biological Properties of Organic-Inorganic Hybrid Calcium Silicate Cements: An In Vitro Study.

Minji Choi, Jiyoung Kwon, Ji-Hyun Jang, Duck-Su Kim, Hyun-Jung Kim

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minji ChoiMedical Science Research Institute, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Jiyoung KwonDepartment of Conservative Dentistry, Kyung Hee University Dental Hospital, Seoul 02447, Republic of Korea.
Ji-Hyun JangDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0002-4672-3381
Duck-Su KimDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0001-9386-6062
Hyun-Jung KimDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0002-7674-9363

Funding

Kyung Hee University 20231138National Research Foundation of Korea (NRF) 2021R1F1A1045987
6 · The paper itself

Abstract

(1) Background: This study aimed to enhance the biological properties of hydraulic calcium silicate cements (HCSCs) by incorporating organic and inorganic components, specifically elastin-like polypeptides (ELPs) and bioactive glass (BAG). We focused on the effects of these composites on the viability, migration, and osteogenic differentiation of human periodontal ligament fibroblasts (hPDLFs). (2) Methods: Proroot MTA was supplemented with 1-5 wt% 63S BAG and 10 wt% ELP. The experimental groups contained various combinations of HSCS with ELP and BAG. Cell viability was assessed using an MTT assay, cell migration was evaluated using wound healing and transwell assays, and osteogenic activity was determined through Alizarin Red S staining and a gene expression analysis of osteogenic markers (

Indexed as

bioactive glasscell migrationcell viabilityelastin-like polypeptidehuman periodontal ligament fibroblastshydraulic calcium silicate cementosteogenesis

Identifiers

PMID39590541
PMCPMC11595442

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.