Evidence map›Paper›PMID 39590340›Full record

ArticleCurrent issues in molecular biology2024

The Role of Cacao Powder in Enhancing Skin Moisture and Reducing Wrinkles: A 12-Week Clinical Trial and In Vitro Study.

Sang Gyu Lee, Ngoc Ha Nguyen, Young In Lee, Inhee Jung, In Ah Kim, Hyunsook Jang, Hoyeon Shin, Ju Hee Lee

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sang Gyu LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-6237-9031
Ngoc Ha NguyenDepartment of Dermatology, University of Medicine and Pharmacy, Ho Chi Minh City 17000, Vietnam.ORCID 0009-0002-4466-9550
Young In LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-6831-7379
Inhee JungGlobal Medical Research Center Co., Ltd., Seoul 06526, Republic of Korea.ORCID 0000-0003-3257-9742
In Ah KimGlobal Medical Research Center Co., Ltd., Seoul 06526, Republic of Korea.
Hyunsook JangLotte R&D Center, Seoul 07594, Republic of Korea.
Hoyeon ShinLotte R&D Center, Seoul 07594, Republic of Korea.ORCID 0009-0008-7485-5438
Ju Hee LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin aging is driven by a combination of internal and external mechanisms, with ultraviolet (UV) radiation being a prominent external factor contributing to photoaging. Photoaging manifests through several signs, including decreased skin hydration, diminished elasticity, coarse wrinkles, and dyspigmentation. Cacao beans, known for their flavonoids and polyphenols, offer potential anti-aging benefits. To explore this, we conducted a study using both in vitro experiments and clinical trials. Our results demonstrated that cacao powder significantly improved skin hydration and moisture retention in both experimental settings. Specifically, in UVB-damaged human dermal fibroblasts (HDFs) and H

Indexed as

cacao powderskin moistureskin senescencewrinkles

Identifiers

PMID39590340
PMCPMC11592858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.