Evidence map›Paper›PMID 39590337›Full record

ArticleCurrent issues in molecular biology2024

Effect of Soy Isoflavone on Prostate Cancer Cell Apoptosis Through Inhibition of STAT3, ERK, and AKT.

Yoon-Jin Lee, Changyeol Lee, Dongsic Choi, Yeji Lee, Sang-Han Lee

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yoon-Jin LeeDepartment of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31511, Republic of Korea.ORCID 0000-0001-6364-1284
Changyeol LeeDepartment of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31511, Republic of Korea.
Dongsic ChoiDepartment of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31511, Republic of Korea.ORCID 0000-0002-2516-5616
Yeji LeeDepartment of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31511, Republic of Korea.
Sang-Han LeeDepartment of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31511, Republic of Korea.

Funding

National Research Foundation (NRF) of Korea NRF-2022R1F1A1069376Soonchunhyang University Research Fund 2024
6 · The paper itself

Abstract

Genistein, an isoflavone found in soybeans, exhibits antioxidant, anti-inflammatory, and anticancer properties. This study explored the molecular mechanisms behind genistein's anticancer effects in prostate cancer DU145 cells. In this study, genistein decreased cell viability, increased annexin V-PE(+) cells, and enhanced the sub-G

Indexed as

apoptosisgenisteinprostate cancerreactive oxygen speciesSTAT3

Identifiers

PMID39590337
PMCPMC11592447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.