Evidence map›Paper›PMID 39590209›Full record

ArticleJournal of cardiovascular development and disease2024

Bleeding Risk of Anticoagulation Reversal Strategies Before Heart Transplantation: A Retrospective Comparative Cohort Study.

Antonio Prieto-Romero, Sara Ibañez-García, Xandra García-González, Javier Castrodeza, Beatriz Torroba-Sanz, Carlos Ortiz-Bautista, Cristina Pascual-Izquierdo, José María Barrio-Gutiérrez, Ángel González-Pinto, Ana Herranz-Alonso and 1 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonio Prieto-RomeroDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0001-8560-1363
Sara Ibañez-GarcíaDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0003-4686-8537
Xandra García-GonzálezDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-6269-7953
Javier CastrodezaDepartment of Cardiology, Hospital General Universitario Gregorio Marañón, CIBER de Enfermedades Cardiovasculares (CIBERV), 28007 Madrid, Spain.ORCID 0000-0002-4779-6849
Beatriz Torroba-SanzDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0003-2574-4076
Carlos Ortiz-BautistaDepartment of Cardiology, Hospital General Universitario Gregorio Marañón, CIBER de Enfermedades Cardiovasculares (CIBERV), 28007 Madrid, Spain.ORCID 0000-0002-4874-715X
Cristina Pascual-IzquierdoDepartment of Hematology, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0001-5442-4886
José María Barrio-GutiérrezDepartment of Anaesthesia, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.
Ángel González-PintoDepartment of Cardiac Surgery, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.
Ana Herranz-AlonsoDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-5517-0248
María Sanjurjo-SáezDepartment of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.

Funding

Instituto de Investigación Sanitaria Gregorio Marañón (IISGM) X
6 · The paper itself

Abstract

Heart transplantation (HT) poses high bleeding risks, especially for patients on anticoagulation. This study evaluates the use of idarucizumab for dabigatran (DBG) reversal compared to vitamin K antagonist (VKA) strategies in HT. A retrospective analysis of HT patients from January 2018 to December 2022, excluding those requiring ECMO immediately before or after surgery, was conducted. Outcomes included transfusion needs, re-surgery due to bleeding, ICU stay lengths, and 30-day survival. A cost analysis compared the direct expenses of each strategy. Among 34 patients, 20 were on DBG and 14 on VKAs or not anticoagulated. Idarucizumab significantly reduced the number of patients requiring transfusion (

Indexed as

anticoagulation reversalbleeding riskeconomic analysisheart transplantationidarucizumab

Identifiers

PMID39590209
PMCPMC11594878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.