ArticleGels (Basel, Switzerland)2024
Enhancing Medium-Chain Fatty Acid Delivery Through Bigel Technology.
Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Soft Gels in Food Systems: Recent Advances, Applications, and Technological Innovations.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study presents the development and characterization of medium-chain fatty acid (MCFA)-loaded bigels, using coconut oil as the MCFA source. The bigels exhibited high oil binding capacity, ranging from 87% to 98%, effectively retaining MCFAs within the matrix, with lauric acid (C12) being the main component detected within the bigels at 178.32 ± 0.10 mg/g. Physicochemical analysis, including FTIR and scanning electron microscopy, confirmed stable fatty acid incorporation and a cohesive, smooth structure. The FTIR spectra displayed O-H and C=O stretching vibrations, indicating hydrogen bonding within the matrix, while the SEM images showed uniform lipid droplet distribution with stable phase separation. Thermal stability tests showed that the bigels were stable for 5 days at 50 °C, with oil retention and structural integrity unchanged. Rheological testing indicated a solid-like behavior, with a high elastic modulus (G') that consistently exceeded the viscous modulus (G″), which is indicative of a strong internal structure. In simulated gastrointestinal digestion, the bigels achieved significantly higher MCFA retention than the pure oil, particularly in the gastric phase, with recovery percentages of 38.1% for the bigels and 1.7% for the oil (
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Registered trials
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