Evidence map›Paper›PMID 39590059›Full record

ReviewGels (Basel, Switzerland)2024

Hyaluronic Acid-Based Dynamic Hydrogels for Cartilage Repair and Regeneration.

Mingshuo Zhang, Qianwen Ye, Zebo Zhu, Shuanglian Shi, Chunming Xu, Renjian Xie, Yumei Li

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Cartilage-SpecificBiomedicines · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Hydrogel-based neural engineering for skin wound healing.Frontiers in cell and developmental biology · 2026
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingshuo ZhangSchool of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.
Qianwen YeSchool of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.
Zebo ZhuSchool of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.
Shuanglian ShiSchool of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.
Chunming XuJiangxi Provincial Key Laboratory of Tissue Engineering (2024SSY06291), Gannan Medical University, Ganzhou 341000, China.
Renjian XieSchool of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0002-0523-9702
Yumei LiJiangxi Provincial Key Laboratory of Tissue Engineering (2024SSY06291), Gannan Medical University, Ganzhou 341000, China.

Funding

Gannan Medical University QD202136, QD202132Jiangxi Province Thousand Talents Project jxsq2023101065Jiangxi students' platform for innovation and entrepreneurship training program 202310413004Light of Soviet Area Talent Project GZSQZG202302025National Natural Science Foundation of China 52303180,82360542Natural Science Foundation of Jiangxi Provincial 20224BAB214030, 20224BAB216072
6 · The paper itself

Abstract

Hyaluronic acid (HA), an important natural polysaccharide and meanwhile, an essential component of extracellular matrix (ECM), has been widely used in tissue repair and regeneration due to its high biocompatibility, biodegradation, and bioactivity, and the versatile chemical groups for modification. Specially, HA-based dynamic hydrogels, compared with the conventional hydrogels, offer an adaptable network and biomimetic microenvironment to optimize tissue repair and the regeneration process with a striking resemblance to ECM. Herein, this review comprehensively summarizes the recent advances of HA-based dynamic hydrogels and focuses on their applications in articular cartilage repair. First, the fabrication methods and advantages of HA dynamic hydrogels are presented. Then, the applications of HA dynamic hydrogels in cartilage repair are illustrated from the perspective of cell-free and cell-encapsulated and/or bioactive molecules (drugs, factors, and ions). Finally, the current challenges and prospective directions are outlined.

Indexed as

cartilage regenerationcartilage repairhyaluronic acidhydrogels

Identifiers

PMID39590059
PMCPMC11594165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.