Evidence map›Paper›PMID 39590038›Full record

ArticleGels (Basel, Switzerland)2024

Investigation of Tannic Acid Crosslinked PVA/PEI-Based Hydrogels as Potential Wound Dressings with Self-Healing and High Antibacterial Properties.

Nimet Rumeysa Karakuş, Serbülent Türk, Gamze Guney Eskiler, Marat Syzdykbayev, Nurbol O Appazov, Mahmut Özacar

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nimet Rumeysa KarakuşDepartment of Biomedical Engineering, Institute of Natural Sciences, Sakarya University, 54187 Sakarya, Türkiye.ORCID 0000-0002-8121-4523
Serbülent TürkBiomaterials, Energy, Photocatalysis, Enzyme Technology, Nano & Advanced Materials, Additive Manufacturing, Environmental Applications and Sustainability Research & Development Group (BIOENAMS R & D Group), Sakarya University, 54050 Sakarya, Türkiye.ORCID 0000-0003-4284-5397
Gamze Guney EskilerDepartment of Medical Biology, Faculty of Medicine, Sakarya University, 54100 Sakarya, Türkiye.ORCID 0000-0002-2088-9914
Marat SyzdykbayevLaboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Aiteke bi Str., 29A, Kyzylorda 120014, Kazakhstan.ORCID 0000-0002-6069-4644
Nurbol O AppazovLaboratory of Engineering Profile "Physical and Chemical Methods of Analysis", Korkyt Ata Kyzylorda University, Aiteke bi Str., 29A, Kyzylorda 120014, Kazakhstan.ORCID 0000-0001-8765-3386
Mahmut ÖzacarBiomaterials, Energy, Photocatalysis, Enzyme Technology, Nano & Advanced Materials, Additive Manufacturing, Environmental Applications and Sustainability Research & Development Group (BIOENAMS R & D Group), Sakarya University, 54050 Sakarya, Türkiye.ORCID 0000-0002-1783-7275

Funding

This research has been funded by the Limited Liability Partnership "KazEcoChem" Limited Liability Partnership "KazEcoChem"This work was supported by the Scientific Research Projects Commission of Sakarya University 2023-19-43-36
6 · The paper itself

Abstract

This study developed hydrogels containing different ratios of TA using polyvinyl alcohol (PVA) and polyethyleneimine (PEI) polymers crosslinked with tannic acid (TA) for the treatment of burn wounds. Various tests, such as scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), swelling, moisture retention, contact angle, tensile strength, the scratch test, antibacterial activity and the in vitro drug-release test, were applied to characterize the developed hydrogels. Additionally, the hydrogels were examined for cytotoxic properties and cell viability with the WST-1 test. TA improved both the self-healing properties of the hydrogels and showed antibacterial activity, while the added gentamicin (GEN) further increased the antibacterial activities of the hydrogels. The hydrogels exhibited good hydrophilic properties and high swelling capacity, moisture retention, and excellent antibacterial activity, especially to

Indexed as

antibacterial propertiesanti-freezingdrug releasehydrogelself-healingtannic acid

Identifiers

PMID39590038
PMCPMC11593458

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.