Evidence map›Paper›PMID 39590016›Full record

ArticleBiosensors2024

Portable Miniaturized IoT-Enabled Point-of-Care Device for Electrochemical Sensing of Zopiclone in Cocktails.

María Gabriela Mejía-Méndez, Paula C Cifuentes-Delgado, Sergio D Gómez, Crhistian C Segura, Nancy Ornelas-Soto, Johann F Osma

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Gabriela Mejía-MéndezDepartment of Biomedical Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá D.C. 111711, Colombia.ORCID 0009-0008-4804-4527
Paula C Cifuentes-DelgadoDepartment of Biomedical Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá D.C. 111711, Colombia.
Sergio D GómezDepartment of Electrical and Electronic Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá D.C. 111711, Colombia.
Crhistian C SeguraDepartment of Electrical and Electronic Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá D.C. 111711, Colombia.ORCID 0000-0003-1368-8679
Nancy Ornelas-SotoLaboratorio de Nanotecnología Ambiental, Escuela de Ingeniería y Ciencias, Tecnológico de Monterrey, Monterrey 64849, Mexico.
Johann F OsmaDepartment of Biomedical Engineering, Universidad de los Andes, Cra. 1E No. 19a-40, Bogotá D.C. 111711, Colombia.ORCID 0000-0003-2928-3406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study proposes a portable and IoT-based electrochemical point-of-care sensing device for detecting zopiclone in cocktails. The system utilizes an electrochemical laccase biosensor and a potentiostat, offering a low-cost and portable device for detecting this sedative drug in cocktails. The sensor characterization experiments demonstrated the linear behavior of the oxidation and reduction currents for each of the targeted concentrations of zopiclone, enabling their detection and quantification even when mixed with an interfering substance. The proposed system could be used for the in situ analysis of cocktails, providing a valuable tool for monitoring the presence of hypnotic drugs in various social and clinical settings. The study utilized materials and reagents, including zopiclone, lab-made lemon juice, lab-made tequila, and lab-made triple sec, all prepared with reactants obtained in Bogotá, Colombia. The potentiostat used in the system was designed to manage cyclic voltammetry measurements. The electrochemical cells' durability and longevity were also tested and characterized, with all electrodes undergoing 200 tests and their performance degradation varying according to the molecule used. The study concludes that the proposed system offers a valuable tool for detecting and monitoring pharmaceutical substances in various interfering ingredients that build up cocktails. Further research and application of this system can help address the global concern surrounding the administration of hypnotic substances to unknowing consumers through food or drinks to enable robbery and sexual assault.

Indexed as

Azabicyclo CompoundsBiosensing TechniquesElectrochemical TechniquesPiperazinesPoint-of-Care SystemsHumansHypnotics and SedativesInternet of ThingsAzabicyclo CompoundsHypnotics and SedativesPiperazineszopiclonebiosensordate-rape drug detectionelectrochemical analysiszopiclone

Identifiers

PMID39590016
PMCPMC11591615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.