Evidence map›Paper›PMID 39589901›Full record

ArticleRegenerative medicine2024

Bone marrow aspirate concentrate for the treatment of fifth metatarsal head stress fracture: a case report.

Hirotaka Nakagawa, Kristen Mitchell, Walter I Sussman

Abstract readCase Reports
In one paragraph

Article in Regenerative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bedside manufacturing of engineered stem cells using gene therapy foam.Molecular therapy. Methods & clinical development · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hirotaka NakagawaDepartment of Orthopedics & Rehabilitation, Tufts Medical Center 800 Washington Street, Boston, MA 02111, USA.ORCID 0000-0002-7491-4986
Kristen MitchellBoston Sports & Biologics, 20 Walnut St. Suite 14, Wellesley, MA 02481, USA.
Walter I SussmanDepartment of Orthopedics & Rehabilitation, Tufts Medical Center 800 Washington Street, Boston, MA 02111, USA.ORCID 0000-0002-3279-6029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metatarsal head stress fractures pose treatment challenges with no established consensus. In this article, we introduce a percutaneous treatment involving autologous bone marrow aspirate concentrate (BMAC) injection without surgical fixation in a 21-year-old basketball player with a stress fracture of the right fifth metatarsal head. He underwent this procedure following unsuccessful 8 months of conservative treatment. Twelve weeks after the procedure, a CT scan confirmed complete healing, facilitating his return to sports. This innovative method offers a promising alternative, avoiding the associated morbidity of surgical intervention. Further research, comparing refracture rates with surgical options, is warranted to inform treatment decisions for this uncommon injury and validate the efficacy of percutaneous BMAC injection.

Indexed as

Fractures, StressMetatarsal BonesBone Marrow TransplantationHumansMaleYoung Adultautologous bone marrow aspirate concentratecase reportmetatarsal head stress fractureregenerative medicine

Identifiers

PMID39589901
PMCPMC11633430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.