Evidence map›Paper›PMID 39589862›Full record

ArticleACS biomaterials science & engineering2024

Mechanical and Physical Characterization of a Biphasic 3D Printed Silk-Infilled Scaffold for Osteochondral Tissue Engineering.

T Braxton, K Lim, C Alcala-Orozco, H Joukhdar, J Rnjak-Kovacina, N Iqbal, T Woodfield, D Wood, C Brockett, X B Yang

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Article in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T BraxtonSchool of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0009-0003-6510-5962
K LimCReaTE Group, Department of Orthopaedic Surgery, University of Otago Christchurch, Christchurch 8140, New Zealand.ORCID 0000-0002-2486-196X
C Alcala-OrozcoCReaTE Group, Department of Orthopaedic Surgery, University of Otago Christchurch, Christchurch 8140, New Zealand.
H JoukhdarGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, New South Wales 2052, Australia.
J Rnjak-KovacinaGraduate School of Biomedical Engineering, UNSW Sydney, Sydney, New South Wales 2052, Australia.ORCID 0000-0001-6121-4676
N IqbalChemical and Process Engineering, University of Leeds, Leeds LS2 9JT, U.K.
T WoodfieldCReaTE Group, Department of Orthopaedic Surgery, University of Otago Christchurch, Christchurch 8140, New Zealand.ORCID 0000-0002-5428-7575
D WoodBiomaterials and Tissue Engineering Group, Department of Oral Biology, University of Leeds, WTBB, St. James's University Hospital, Leeds LS9 7TF, U.K.
C BrockettSchool of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, U.K.
X B YangBiomaterials and Tissue Engineering Group, Department of Oral Biology, University of Leeds, WTBB, St. James's University Hospital, Leeds LS9 7TF, U.K.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteochondral tissue damage is a serious concern, with even minor cartilage damage dramatically increasing an individual's risk of osteoarthritis. Therefore, there is a need for an early intervention for osteochondral tissue regeneration. 3D printing is an exciting method for developing novel scaffolds, especially for creating biological scaffolds for osteochondral tissue engineering. However, many 3D printing techniques rely on creating a lattice structure, which often demonstrates poor cell bridging between filaments due to its large pore size, reducing regenerative speed and capacity. To tackle this issue, a novel biphasic scaffold was developed by a combination of 3D printed poly(ethylene glycol)-terephthalate-poly(butylene-terephthalate) (PEGT/PBT) lattice infilled with a porous silk scaffold (derived from

Indexed as

Printing, Three-DimensionalSilkTissue EngineeringTissue ScaffoldsAnimalsBombyxCompressive StrengthFibroinsHumansMaterials TestingMesenchymal Stem CellsFibroinsSilk3D printingBiphasic scaffoldCartilage regenerationOsteochondralSilk fibroinTissue Engineering

Identifiers

PMID39589862
PMCPMC11632666

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.