Evidence map›Paper›PMID 39589671›Full record

ArticleArchives of pharmacal research2024

Prediction of human pharmacokinetic parameters incorporating SMILES information.

Jae-Hee Kwon, Ja-Young Han, Minjung Kim, Seong Kyung Kim, Dong-Kyu Lee, Myeong Gyu Kim

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of pharmacal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jae-Hee KwonGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Ja-Young HanGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Minjung KimGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Seong Kyung KimGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Dong-Kyu LeeCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Myeong Gyu KimGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea. kimmg@ewha.ac.kr.ORCID http://orcid.org/0000-0002-5593-7672

Funding

National Research Foundation of Korea NRF-2021R1C1C1013177
6 · The paper itself

Abstract

This study aimed to develop a model incorporating natural language processing analysis for the simplified molecular-input line-entry system (SMILES) to predict clearance (CL) and volume of distribution at steady state (V

Indexed as

PharmacokineticsAlgorithmsAnimalsHumansMachine LearningModels, BiologicalNatural Language ProcessingPharmaceutical PreparationsPharmaceutical PreparationsClearanceMachine learningPharmacokineticsSMILESVolume of distribution

Identifiers

PMID39589671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.