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ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Factors associated with functional ability in patients with esophageal cancer undergoing chemoradiotherapy: a prospective longitudinal study.

Han-Yen Lee, Bing-Shen Huang, Chen-Kan Tseng, Ping-Ching Pai, Tsung-Min Hung, Yin-Kai Chao, Shu-Ching Chen

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Symptom distress and fear of progression associated with quality of life in multiple myeloma patients receiving treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Han-Yen LeeDepartment of Nursing, Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, Republic of China.
Bing-Shen HuangSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China.
Chen-Kan TsengSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China.
Ping-Ching PaiSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China.
Tsung-Min HungSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China.
Yin-Kai ChaoSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, Republic of China.
Shu-Ching ChenDepartment of Radiation Oncology, and Proton and Radiation Therapy Center, Chang Gung Medical Foundation, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan, Republic of China. shuching@gw.cgust.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDuring and after treatment, esophageal cancer (EC) patients experience changes in body mass index (BMI), performance status, nutrition status, symptom distress, and physical fitness. This study aims to evaluate temporal changes and their associated factors in BMI, performance status, nutrition status, symptom distress, physical fitness, and functional ability in EC patients during and after treatment.

methodsThis prospective longitudinal study recruited EC patients from a medical center in Northern Taiwan. The 100 EC patients were assessed before treatment (T0), 1 month after starting treatment (T1), 3 months after starting treatment (end of treatment) (T2), and 6 months after starting treatment (T3). Generalized estimating equation analysis was used to determine the factors associated with changes in functional ability over time.

resultsPatient nutrition status was lowest before treatment and then increased by 6 months after treatment. Symptom distress slightly decreased from before treatment to 3 months after treatment, rising at 6 months after treatment but not reaching baseline (T0). Functional ability increased from before treatment to 1 month after treatment and then declined at 3 months after starting treatment, increasing at 6 months to below baseline (T0). Patients who had a BMI less than 25 kg/m

conclusionBMI, level of physical activity, and the degree of physical fitness were the important factors associated with functional ability in EC patients. Healthcare professionals should design patient-tailored prehabilitation programs in advance to strengthen physical fitness.

Indexed as

Body Mass IndexChemoradiotherapyEsophageal NeoplasmsNutritional StatusAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedPhysical FitnessProspective StudiesTaiwanTime FactorsEsophageal cancerLongitudinal studiesNutritional statusPhysical abilityPhysical fitnessSymptom distress

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.